Physiological Adjustment of Arterial Blood Gases and Bicarbonate ION During Pregnancy in Human

Authors

  • Dipok Kumar Sunyal Assistant Professor, Department of Physiology, Enam Medical College, Savar, Dhaka
  • Md Ruhul Amin Professor, Department of Physiology, Dhaka Medical College, Dhaka
  • Abida Ahmed Professor, Department of Physiology, Comilla Medical College, Comilla
  • Mir Rabaya Akhter Assistant Registrar, Department of Gynaecology and Obstetrics, Moulana Bhasani Medical College and Hospital, Dhaka
  • Golam Morshed Molla Assistant Professor, Department of Biochemistry, Enam Medical College, Savar, Dhaka
  • ABM Omar Faruque Assistant Professor, Department of Anatomy, Tairunnessa Memorial Medical College, Gazipur

DOI:

https://doi.org/10.3329/bjpp.v23i1.5724

Keywords:

arterial blood gases

Abstract

In the present study the partial pressure of oxygen (PaO2), carbon dioxide (PaCO2) and bicarbonate ion (HCO3-) in arterial blood were estimated in 32 women in Dhaka city. For this purpose a total of 32 women subjects with age ranged from 25 years to 35 years without any recent history of respiratory diseases were selected. Of those, 8 healthy non-pregnant women were included as control and 24 normal pregnant women as experimental group. The PaO2, PaCO2 and HCO3- were estimated during the first, second and third trimester by using 'easy blood gas auto analyzer'. The PaO2 was significantly higher during entire pregnancy period. However, the PaCO2 and HCO3- were significantly lower in first, second and third trimester of pregnant women than that of non-pregnant women. There were no statistically significant difference of PaO2, PaCO2 and HCO3- ion among first trimester, second trimester and third trimester. The progressively increased PaO2, decreased PaCO2 and HCO3- ion throughout the pregnancy is possibly due to the effect of progesterone causing hyperventilation.

DOI: 10.3329/bjpp.v23i1.5724

Bangladesh J Physiol Pharmacol 2007; 23(1&2) : 10-12

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How to Cite

Sunyal, D. K., Amin, M. R., Ahmed, A., Akhter, M. R., Molla, G. M., & Faruque, A. O. (2010). Physiological Adjustment of Arterial Blood Gases and Bicarbonate ION During Pregnancy in Human. Bangladesh Journal of Physiology and Pharmacology, 23(1), 10–12. https://doi.org/10.3329/bjpp.v23i1.5724

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Original Articles