Bioactivity guided cytotoxic activity of Clitoria ternatea utilizing brine shrimp lethality bioassay

  • AKM Shahidur Rahman Senior Lecturer, Department of Pharmacology & Therapeutics, Kumudini Women's Medical College, Mirzapur, Tangali
  • Oqna; Arslan Professor & Chairman, Department of Bio-chemistry, BSMMU, Shahbag, Dhaka
  • Rama Saha Assistant Professor, Department of Pharmacology & Therapeutics, Faridpur Medical College, Faridpur
  • Nirupama Talukder Assistant Professor, Department of Forensic Medicine, Moulana Bhasani Medical College, Uttara, Dhaka
  • SMA Khaleque Associate Professor, Department of Microbiology, Moulana Bhasani Medical College, Uttara, Dhaka
  • Husne Ara Ali Ph. D Researcher, Department of Clinical Pharmacy & Pharmacology, University of Dhaka, Dhaka
Keywords: Clitoria ternatea

Abstract

The crude methanol extract of leaves, seeds and stem-bark of Clitoria ternatea demonstrated a significant cytotoxic activity in a brine shrimp lethality bioassay test. The LC50 values of the crude methanol extract of leaves, seeds and stem-bark were found to be 25.82, 110.92, 179.89 μgm/ml respectively Among them crude methanol extract of leaves (25.82 μgm/ml) and methanol fraction of leaves (22.28 μgm/ml) showed a very promising cytotoxic activity. Further studies have been suggested to discover a novel bioactive compound from methanol fraction of leaves of Clitoria ternatea.  

DOI: 10.3329/bjpp.v22i1.3564

Bangladesh J Physiol Pharmacol 2006; 22(1/2) : 18-21

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How to Cite
Rahman, A., Arslan, O., Saha, R., Talukder, N., Khaleque, S., & Ali, H. (1). Bioactivity guided cytotoxic activity of Clitoria ternatea utilizing brine shrimp lethality bioassay. Bangladesh Journal of Physiology and Pharmacology, 22(1), 18-21. https://doi.org/10.3329/bjpp.v22i1.3564
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Original Articles