The effect of plant hormone indoleacetic acid (IAA) on hematological and biochemical parameters in mice

  • MH Morshed Department of Chemistry, Khulna University of Engineering and Technology, Khulna-9203
  • M Shamm Hossain Microbiology and Biotechnology Laboratory, Department of Pharmacy, Rajshahi University, Rajshahi-6205
  • M Anwar Habib Department of Pharmacology and Therapeutics, Rajshahi Medical College, Rajshahi
  • MM Moinuddin Ahmed Department of Physiology, Khulna Medical College, Khulna
  • M Ibrahim BCSIR Laboratories, Binodpur Bazar, Rajshahi-6206
  • M Umar Ali Department of Chemistry, Rajshahi University; Rajshahi-6205
  • M Azizul Islam
Keywords: indoleacetic acid

Abstract

The subacute toxicity of plant hormone indoleacetic acid (IAA) was studied on Swiss albino mice. The studies include the gross general observation such as changes in body weight, hematological profiles [total count of red blood cells (RBC) and white blood cells (WBC), differential count of WBC, platelet count, hemoglobin (Hb)%], biochemical parameters of blood [serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), serum alkaline phospatase(SALP), creatinine] and histopathology of the liver, kidney, lung, spleen, heart and brain of both control and experimental day-1 for consecutive 14 days, showed no significant change of hematological and biochemical parameters. No abnormalities were also found in the histopathology of the liver, kidney, lung, spleen, heart and brain in the experimental group of animals following same dose when compared with control group. This preliminary toxicological study suggests that the plant hormone indoleacetic acid (IAA) may be used safely for agricultural purposes and as an external preservative

DOI: 10.3329/bjpp.v22i1.3561

Bangladesh J Physiol Pharmacol 2006; 22(1/2) : 5-8

 

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How to Cite
Morshed, M., Hossain, M., Habib, M., Ahmed, M., Ibrahim, M., Ali, M., & Islam, M. (1). The effect of plant hormone indoleacetic acid (IAA) on hematological and biochemical parameters in mice. Bangladesh Journal of Physiology and Pharmacology, 22(1), 5-8. https://doi.org/10.3329/bjpp.v22i1.3561
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Original Articles