Tail suspension test to evaluate the antidepressant activity of experimental drugs
Keywords:Antidepressant, Tail suspension test
Tail suspension test (TST) is a common behavioral paradigm used to evaluate the antidepressant activity of experimental drugs. Like the forced swimming test, in this test the animals are set in an inescapable yet modestly distressing circumstance. In the tail suspension test, the extent of immobility is thought to be associated with the depressive-like condition of the animal and is significantly diminished by antidepressant drugs.
Video clips of Methodology:
Pre-experiment: 53 sec Full Screen Alternate
Experiment: 7 min 31 sec Full Screen Alternate
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