Tail suspension test to evaluate the antidepressant activity of experimental drugs

Authors

DOI:

https://doi.org/10.3329/bjp.v11i2.26517

Keywords:

Antidepressant, Tail suspension test

Abstract

Tail suspension test (TST) is a common behavioral paradigm used to evaluate the antidepressant activity of experimental drugs. Like the forced swimming test, in this test the animals are set in an inescapable yet modestly distressing circumstance. In the tail suspension test, the extent of immobility is thought to be associated with the depressive-like condition of the animal and is significantly diminished by antidepressant drugs.

Video clips of Methodology:

Pre-experiment: 53 sec   Full Screen   Alternate

Experiment: 7 min 31 sec   Full Screen   Alternate

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Author Biography

Muhammad Aslam, Department of Pharmacology, Faculty of Pharmacy, Ziauddin University, Karachi 75600

Research Scholar

References

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Published

2016-03-13

How to Cite

Aslam, M. “Tail Suspension Test to Evaluate the Antidepressant Activity of Experimental Drugs”. Bangladesh Journal of Pharmacology, vol. 11, no. 2, Mar. 2016, pp. 292-4, doi:10.3329/bjp.v11i2.26517.

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Section

Visual Experiment