Effect of Chlorhexidine Cleansing of Umbilical Cord for Prevention of Infection

  • Md Khairuzzaman Assistant Professor, Department of Paediatrics, Shaheed Suhrawardy Medical College, Dhaka
  • MA Mannan Professor and Chairman, Department of Neonatology, Banga bandhu Shiekh Mujib Medical University, Dhaka
  • Abdul Matin Associate Professor, Department of Paediatrics, Shaheed Suhrawardy Medical College, Dhaka
  • Mst Monjuman Ara Sarker Junior Consultant (Gynaecology & Obstetrics), Upzilla Health Complex, Dhamrai, Dhaka
  • Nihar Ranjan Sarker Associate Professor, Department of Paediatrics, Shaheed Suhrawardy Medical College, Dhaka
  • MA Rouf Assistant Professor, Department of Paediatrics, Shaheed Suhrawardy Medical College, Dhaka
  • Mohmmad Shahidullah Professor, Department of Neonatology, Bangabandhu Shiekh Mujib Medical University, Dhaka
Keywords: Chlorhexidine, Umbilical Cord, infection prevention, cleansing

Abstract

Background: Chlorhexidine cleansing of the cord can reduce neonatal mortality among newborns.

Objective: The aim of study was to determine the effect of cord cleansing with chlorhexidine in reduction of umbilical infection among newborns in hospital settings.

Methodology: This randomized controlled trial was carried out between April 2013 to July 2014 and 510 newborns were randomly assigned within a tertiary level hospital in Bangladesh to receive 1 of 3 cord care regimens single cord cleansing with 4% chlorhexidine(Group-1), multiple cord cleansing with 4% chlorhexidine (Group-2)  and clean and dry cord care (Group-3 : control).

Results: The risk of umbilical cord infection (omphalitis) was significantly reduced in both the single (Relative risk [RR] 0.15 [95% CI] 0.008-0.93) and multiple chlorhexidine cleansing group (RR 0.37 [95% CI] 0.04- 0.99) compared to the dry cord care group.  The risk of omphalitis was not significantly different between multiple and single chlorhexidine cleansing group (RR 3.14 [0.13-76.54]).

Conclusion: Chlorhexidine significantly reduce the risk of umbilical infection in both single and multiple cord cleansing neonates.

Bangladesh Journal of Infectious Diseases 2017;4(2):35-39

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Abstract
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PDF
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Published
2018-08-03
How to Cite
Khairuzzaman, M., Mannan, M., Matin, A., Sarker, M. M., Sarker, N., Rouf, M., & Shahidullah, M. (2018). Effect of Chlorhexidine Cleansing of Umbilical Cord for Prevention of Infection. Bangladesh Journal of Infectious Diseases, 4(2), 35-39. https://doi.org/10.3329/bjid.v4i2.37683
Section
Original Articles