Comparative Dissolution Study of Different Brands of Amoxicillin Trihydrate Capsules Available in Bangladesh

  • Naz Hasan Huda Department of Pharmacy, Stamford University Bangladesh
  • Yeakuty Marzan Jhanker Pharmacy Discipline, Khulna University, Khulna
  • AFM Shahid-Ud-Daula Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali
  • Most Nazma Parvin Department of Pharmacy, Stamford University Bangladesh
  • Shammy Sarwar Department of Pharmacy, Stamford University Bangladesh
Keywords: In vitro Dissolution, Market preparations, Amoxicillin Trihydrate, Capsule, National Brand, Multinational Brand

Abstract

Commercially available twenty national and four multinational brands of Amoxicillin Trihydrate capsules were
studied  in water  for 60 minutes using USP reference dissolution apparatus. All, except  two national brands
(Code: NB-8 and NB-15); complied with  the USP  in vitro dissolution specification  for drug release (not  less
than 80% of the labelled amount of amoxicillin trihydrate should be dissolved in 60 minutes). Drug releases
from those two brands were 75% and 67% respectively within the specified time period.
 
Key words:
In vitro Dissolution; Market preparations; Amoxicillin Trihydrate; Capsule; National Brand;
Multinational Brand.

DOI: 10.3329/sjps.v2i2.5827

Stamford Journal of Pharmaceutical Sciences Vol.2(2) 2009: 72-75

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How to Cite
Huda, N., Jhanker, Y., Shahid-Ud-Daula, A., Parvin, M., & Sarwar, S. (1). Comparative Dissolution Study of Different Brands of Amoxicillin Trihydrate Capsules Available in Bangladesh. Stamford Journal of Pharmaceutical Sciences, 2(2), 72-75. https://doi.org/10.3329/sjps.v2i2.5827
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Research Articles