Chemical and Biological Investigation of Leaves of <i>Polygonum plebejum</i>

  • Md Kamrul Hasan Department of Natural Science, Stamford University Bangladesh
  • Abul Kalam Lutful Kabir Department of Pharmacy, Stamford University Bangladesh
  • Sabyasachy Mistry Department of Natural Science, Stamford University Bangladesh
Keywords: Polygonum plebejum, Polygonaceae, Stigmasterol, Cytotoxicity

Abstract

The cytotoxic and antimicrobial activity of methanol crude extract and column fractions of the extract of the
leaves of P. plebejum were examined by brine shrimp lethality bioassay and disc diffusion method
respectively. The extracts showed significant cytotoxic as well as antimicrobial activities. Silica gel column
chromatography of methanol extract of P. plebejum afforded a steroid. The structure was elucidated on the
basis of spectral analysis, including 1H NMR and 13C NMR and also by comparing with data in the literature.
 
Key words: Polygonum plebejum; Polygonaceae; Stigmasterol; Cytotoxicity.

DOI: 10.3329/sjps.v2i2.5826

Stamford Journal of Pharmaceutical Sciences Vol.2(2) 2009: 66-71

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How to Cite
Hasan, M., Kabir, A., & Mistry, S. (1). Chemical and Biological Investigation of Leaves of <i>Polygonum plebejum</i&gt;. Stamford Journal of Pharmaceutical Sciences, 2(2), 66-71. https://doi.org/10.3329/sjps.v2i2.5826
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Research Articles