Antibacterial Screening and Phytochemical investigation of bark extracts of <i>Acacia jacquemontii</i> Benth.
AbstractAcacia jacquemontii was assessed for active principles to ascertain the rationale for its use in traditional
medicine. Preliminary phytochemical screening of the stem bark extracts showed that it possessed the active
principles - alkaloids, glycosides, saponins, terpenoids and tannins. The antimicrobial activity of the extracts
was assayed against pathogenic strains of Bacillus cereus, Bacillus pumilus, Escherichia coli, Pseudomonas
aeruginosa, Staphylococcus aureus, S. pyrogenes, and Candida albcans using the agar diffusion method.
The plant extract exhibited antimicrobial activity against all the test microorganisms. B. cereus and B. pumilus
were the most susceptible to the plant extract while Candida albicans was the most resistant. The minimum
inhibitory concentration of the stem bark extract of the plant ranged between 30 and 50 mg/ml while the
minimum bactericidal concentration ranged between 35 and 60 mg/ml. A. jacquemontii could be a potential
source of antimicrobial agents.
Key words: Antibacterial; Antifungal; Baonli; Medicinal plants.
Stamford Journal of Pharmaceutical Sciences Vol.2(2) 2009: 21-26
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