Aripiprazole is effective in hyperprolactinemia secondary to use of Fluphenazine

  • Smit Shah MS-4, Rutgers Robert Wood Johnson Medical School, New Jersey
  • Pooja Shah Resident Physician, Delaware Psychiatric Center, Delaware
  • Salman Salaria Resident Physician, Delaware Psychiatric Center, Delaware & Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD
  • Osman Salaria Resident Physician Mount Sinai Medical Center of Florida, Florida
Keywords: Hyperprolactinemia, Fluphenazine, Aripiprazole, Hallucinations, Prolactin

Abstract

Aripiprazole is drug that acts as a partial agonist at D2 and 5-HT1A receptors and antagonist at 5-HT2A receptor. It modulates the neurotransmission over activity on the dopaminergic mesolimbic pathway which is responsible for positive symptoms of Schizophrenia. Dopamine antagonism is the mechanism of action of first generation antipsychotics. In this paper we discuss an interesting case in which Aripiprazole was effective in decreasing Prolactin levels which was elevated secondary to previous Fluphenazine use.

South East Asia Journal of Public Health Vol.7(2) 2017: 40-42

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Abstract
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PDF
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Published
2018-11-28
How to Cite
Shah, S., Shah, P., Salaria, S., & Salaria, O. (2018). Aripiprazole is effective in hyperprolactinemia secondary to use of Fluphenazine. South East Asia Journal of Public Health, 7(2), 40-42. https://doi.org/10.3329/seajph.v7i2.38855
Section
Case Study