Prevalence and Antimicrobial Susceptibility Pattern of Klebsiella Pneumoniae Isolated from Various Clinical Specimens in a Tertiary Care Hospital in Bangladesh

Authors

  • Suraiya Jahan Sonia Lecturer, Department of Physio-Therapy and Occupational Therapy, National Institute of Traumatology and Orthopaedic Rehabilitation (NITOR), Sher-E-Bangla Nagar, Dhaka, Bangladesh
  • Shadia Afroz Medical Officer, Department of Microbiology, National Institute of Kidney Diseases and Hospital (NIKDU), Sher-E-Bangla Nagar, Dhaka, Bangladesh
  • - Md Rasheduzzaman Assistant Professor, Department of Microbiology, National Institute of Kidney Diseases and Hospital (NIKDU), Sher-E-Bangla Nagar, Dhaka, Bangladesh
  • Kazi Hafiz Uddin Assistant Professor, Department of Neurosurgery, National Institute of Neurosciences and Hospital (NINS), Sher-E-Bangla Nagar, Dhaka, Bangladesh
  • SM Shamsuzzaman PhD Professor and Head, Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/medtoday.v32i2.48821

Keywords:

Antimicrobial susceptibility, Klebsiella pneumoniae, Various clinical specimens, Strict antimicrobial policy

Abstract

Introduction:Klebsiella pneumoniae are common causative agents of various infections and are of great concern for developing resistance against commonly prescribed antibiotics. This study gives an account of isolation of K. pneumoniae from various clinical specimens and their antimicrobial susceptibility, in a tertiary care hospital of Bangladesh.

Materials and Methods: Various clinical specimens like urine, wound swab, sputum, blood and endotracheal aspirates were collected and processed for isolation of K. pneumoniae followed by their antimicrobial susceptibility testing.

Results: Among the 316 samples that yielded culture positivity, K. pneumoniae were identified as second most common organism. The highest yield of K. pneumoniae (37.33%) were observed from wound swab followed by sputum (26.67%). Most of the isolates were resistant to sulphamethoxazole-trimethoprim (90.67%) and ceftriaxone (90.67%) followed by cefotaxime (89.33%), ceftazidime (89.33%) and cefuroxime (89.33%). The most sensitive antibiotic for the isolates was tigecycline.

Conclusion: Isolated K. pneumoniae showed resistance to commonly prescribed antibiotics, which is very alarming and showing the importance on continuous monitoring and strict antimicrobial policy.

Medicine Today 2020 Vol.32(2): 95-99

Downloads

Download data is not yet available.
Abstract
222
PDF
321

Downloads

Published

2020-08-29

How to Cite

Sonia, S. J., Afroz, S., Md Rasheduzzaman, .-., Uddin, K. H., & Shamsuzzaman, S. (2020). Prevalence and Antimicrobial Susceptibility Pattern of Klebsiella Pneumoniae Isolated from Various Clinical Specimens in a Tertiary Care Hospital in Bangladesh. Medicine Today, 32(2), 95–99. https://doi.org/10.3329/medtoday.v32i2.48821

Issue

Section

Original Articles