Disseminated Histoplasmosis in a Patient with Advanced HIV Disease - Lessons Learnt from Bangladesh

Authors

  • Md Mostaq Pervez ICDDR,B, Dhaka
  • Brian Cobb ICDDR,B, Dhaka
  • Nashaba Matin ICDDR,B, Dhaka
  • Lubaba Shahrin ICDDR,B, Dhaka
  • Evelyn R Ford National Institutes of Health, Fogarty International Clinical Research Scholars Program, Vanderbilt University Institute for Global Health, Nashville, TN
  • Mark Pietroni ICDDR,B, Dhaka

DOI:

https://doi.org/10.3329/jhpn.v28i3.5561

Keywords:

Case studies, Histoplasma capsulatum, Histoplasmosis, HIV, Tuberculosis, Bangladesh

Abstract

Histoplasmosis is a systemic fungal disease, also known as Darling’s disease, caused by the dimorphic fungus
Histoplasma capsulatum. It is usually self-limiting or localized in immunecompetent individuals whereas
in patients with acquired immune deficiency syndrome (AIDS), it occurs in the disseminated form in 95%
of cases. Although histoplasmosis predominates in the Americas (United States and Latin America, including
Brazil) as an important infection among AIDS patients, it is not common in Bangladesh. In contrast,
tuberculosis is extremely common in Bangladesh, with an estimated prevalence of 387 per 100,000 people.
Here, a confirmed case of disseminated histoplasmosis is reported in Bangladesh in a known HIV-positive
patient, which was initially suspected to be extrapulmonary tuberculosis.

Key words: Case studies; Histoplasma capsulatum; Histoplasmosis; HIV; Tuberculosis; Bangladesh

DOI: 10.3329/jhpn.v28i3.5561

J HEALTH POPUL NUTR 2010 Jun;28(3):305-307

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How to Cite

Pervez, M. M., Cobb, B., Matin, N., Shahrin, L., Ford, E. R., & Pietroni, M. (2010). Disseminated Histoplasmosis in a Patient with Advanced HIV Disease - Lessons Learnt from Bangladesh. Journal of Health, Population and Nutrition, 28(3), 305–307. https://doi.org/10.3329/jhpn.v28i3.5561

Issue

Vol. 28 No. 3 (2010)

Section

Case studies