Seropositivity of Toxoplasmosis in Antenatal Women with Bad Obstetric History in a Tertiary-care Hospital of Andhra Pradesh, India

Authors

  • Munmun Das Sarkar Burdwan Medical College, Burdwan, West Bengal
  • B Anuradha Mamata Medical College, Khammam, Andhra Pradesh
  • Neelam Sharma Mamata Medical College, Khammam, Andhra Pradesh
  • Rabindra Nath Roy Burdwan Medical College, Burdwan, West Bengal

DOI:

https://doi.org/10.3329/jhpn.v30i1.11287

Keywords:

Bad obstetric history, Case-control studies, Descriptive studies, Seroprevalence, Toxoplasma gondii, Toxoplasmosis, India

Abstract

Toxoplasmosis is a well-documented cause of bad obstetric history (BOH) and a major reason of congenitally- acquired infection. The study was conducted to determine the seropositivity of toxoplasmosis in women with BOH, attending the antenatal clinic of the Mamata General Hospital, Khammam, Andhra Pradesh, India. The study subjects included 105 antenatal women with BOH and 105 antenatal women who had previous normal deliveries. A serological evaluation was carried out to determine the presence of Toxoplasma gondii-specific IgG and IgM antibodies, using commercial diagnostic kits, by the enzyme-linked immunosorbent assay method. The seropositivity for Toxoplasma was 49.52% in the study group compared to 12.38% in the control group. The difference in seropositivity was significant (p=0.00). The seroprevalence gradually increased with advancing age. Abortion (51.92%) was the commonest form of pregnancy wastage, followed by stillbirths (36.53%) and premature deliveries (7.69%). The seropositivity of toxoplasmosis was significantly higher in the study group than that in the control group, and the seropositivity played an important role in determining the foetal outcome. Considering the subclinical pattern of infection, routine serological test is recommended for all pregnant women for both IgG and IgM antibodies

 

DOI: http://dx.doi.org/10.3329/jhpn.v30i1.11287

 

J HEALTH POPUL NUTR 2012 Mar;30(1):87-92

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Published

2012-07-18

How to Cite

Sarkar, M. D., Anuradha, B., Sharma, N., & Roy, R. N. (2012). Seropositivity of Toxoplasmosis in Antenatal Women with Bad Obstetric History in a Tertiary-care Hospital of Andhra Pradesh, India. Journal of Health, Population and Nutrition, 30(1), 87–92. https://doi.org/10.3329/jhpn.v30i1.11287

Issue

Section

Review Article