Diagnostic Evaluation of Haematological Diseases Based on Bone Marrow Examination

Authors

  • Md Rezaul Karim Chowdhury Associate Professor, Department of Haematology, Enam Medical College & Hospital, Savar, Dhaka
  • Md Mahbub Hossain Associate Professor, Department of Medicine, Enam Medical College & Hospital, Savar, Dhaka
  • Shafayet Hossain Riyan Registrar, Department of Medicine, Enam Medical College & Hospital, Savar, Dhaka
  • Mohammad Al Tarique Assistant registrar, Department of pulmonology, Enam Medical College & Hospital, Savar, Dhaka

DOI:

https://doi.org/10.3329/jemc.v11i1.63171

Keywords:

Bone marrow examination; Haematological disorders; Pancytopenia; Acute myelogenous leukaemia

Abstract

Background: Bone marrow examination is a safe invasive procedure and can provide sufficient explanation for unexplained cytopenias, leukaemia and other haematological disorders including metastases to the marrow by detailed morphological description of the marrow elements.

Objective: To see the importance of bone marrow examination for the diagnosis of haematological disorders.

Materials and Methods: It was a descriptive cross-sectional study comprising 196 patients who underwent bone marrow examination for evaluation of haematological disorders in the Department of Haematology, Enam Medical College and Hospital during the period of July 2012 to December 2019.

Results: Total number of cases were 196, male to female ratio was 1.56:1 and majority of the patients were >18 years of age (84.69%). Common indications for bone marrow examination were pancytopenia (33.67%) and diagnosis of leukaemia/ myeloproliferative neoplasm (23.98%). In our study, haematological conditions were 79.08%. Among these malignant conditions were 55.10% and nonmalignant conditions were 23.98%. Aplastic anaemia (14.29%) and immune thrombocytopenia (7.65%) were the most common nonmalignant disorders. Common malignant disorders were acute myelogenous leukaemia (20.41%) and multiple myeloma (9.69%).

Conclusion: Bone marrow examination is a simple and effective procedure in reaching the final diagnosis of haematological diseases.

J Enam Med Col 2021; 11(1): 34-38

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Published

2023-02-02

How to Cite

Chowdhury, M. R. K., Hossain, M. M., Riyan, S. H., & Tarique, M. A. . (2023). Diagnostic Evaluation of Haematological Diseases Based on Bone Marrow Examination. Journal of Enam Medical College, 11(1), 34–38. https://doi.org/10.3329/jemc.v11i1.63171

Issue

Vol. 11 No. 1 (2021)

Section

Original Articles

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