Efficacy of Immunodiagnosis of Falciparum Malaria at Different Levels of Parasitemia

Authors

  • Mejbah Uddin Ahmed Department of Microbiology, Enam Medical College, Savar, Dhaka
  • Mohammad Akram Hossain Department of Microbiology, Mymensingh Medical College, Mymensingh
  • Abul Hossain Khan Department of Microbiology, Khwaja Younus Ali Medical College, Enayetpur, Sirajgonj
  • Salah Uddin Ahmed Department of ENT, Combined Military Hospital, Dhaka Cantonment, Dhaka

DOI:

https://doi.org/10.3329/jemc.v3i2.16130

Keywords:

Immunodiagnosis, Severe malaria, Hyperparasitemia,

Abstract

Background: Among the several human species of malarial parasites, Plasmodium falciparum can cause severe infection and if left untreated, there may be fatal complications. Early diagnosis and prompt treatment have been proposed to reduce the morbidity and mortality from malaria.

Objective: To assess the diagnostic efficacy of antigen detection by immunochromatographic test (ICT) at different levels of parasitemia for diagnosis of malaria.

Materials and Methods: This study was carried out in the department of Microbiology, Mymensingh Medical College for a period of one year from July 2005 to June 2006. A total of 98 clinically suspected malaria patients were included in this study. Peripheral blood films (PBF) were examined under microscope and parasite count/?L of blood was performed. Subsequently ICT for malaria antigen was done for each case.

Results: Out of 59 cases positive by microscopic examination of blood films, 54 cases had parasitemia >600 parasites/?L of blood and all these cases were positive by ICT for malaria antigen. Rest 5 cases showed parasitemia <600 parasites/?L of blood and one case was found positive by ICT for malaria antigen.

Conclusion: Immunochromatographic test can be used for early diagnosis of malaria with hyperparasitemia, especially for cerebral malaria.

Journal of Enam Medical College; Vol 3 No 2 July 2013; Page 88-90

DOI: http://dx.doi.org/10.3329/jemc.v3i2.16130

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Published

2013-08-07

How to Cite

Ahmed, M. U., Hossain, M. A., Khan, A. H., & Ahmed, S. U. (2013). Efficacy of Immunodiagnosis of Falciparum Malaria at Different Levels of Parasitemia. Journal of Enam Medical College, 3(2), 88–90. https://doi.org/10.3329/jemc.v3i2.16130

Issue

Vol. 3 No. 2 (2013)

Section

Original Articles

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