Role of Serum Ascites Albumin Gradient In The Etiologic Diagnosis of Ascites

Authors

  • Mohammed Masudul Hassan Khan Assistant Professor, Department of Medicine Dhaka Medical College, Dhaka
  • Farzana Rahman Assistant Professor, Department of Medicine Dhaka Medical College, Dhaka
  • Mohammad Mostafa Kamal Assistant Professor, Department of Medicine Dhaka Medical College, Dhaka
  • Farah Momtaz Assistant Professor, Department of Medicine, Dr Sirajul Islam Medical College, Dhaka
  • Md Ismail Patwary Professor, Department of Medicine, Sylhet women s Medical College, Sylhet
  • Md Khairul Islam Junior consultant department of medicine Dhaka medical college hospital

DOI:

https://doi.org/10.3329/jdmc.v31i1.65486

Keywords:

Ascites, Cirrhosis, SerumAlbumin, Ascitic fluid Albumin

Abstract

Background: Classification based on ascitic fluid protein has been challenged on several occasions in diverse clinical situations, including cirrhotic patients on extended diuretic treatment, cardiac ascites, 1/3 individuals with malignant ascites, spontaneous bacterial peritonitis, and even normal ascitic fluid.

Objective: The study’s objective was to observe the role of serum ascites albumin gradient (SAAG) in diagnosing Ascites.

Methods: This cross-sectional observational study was conducted at the Department of Medicine, Sylhet M.A.G. Osmani Medical College Hospital, Bangladesh. with a total of 100 participants with ascites following the inclusion and exclusion criteria of the study.

Result: The most prevalent cause of ascites was cirrhosis, observed in 56% of the participants. Among the 56 cirrhosis patients, mean ± S.D. values of AFTP, AFAlb, SAlb, and SAAG were 2.1±1.2, 0.8±0.6, 3.1±0.7, and 2.2±0.7 respective units accordingly. According to ascitic fluid albumin values, a statistically significant relation was observed between cirrhosis and tuberculosis (P<0.01) and cirrhosis vs malignancy (P<0.01) cases. According to serum ascitic albumin gradient values, a similar significant association was also found between cirrhosis vs tuberculosis (P<0.01) and cirrhosis vs malignancy (P<0.01) cases.

Conclusion: SAAG is an essential laboratory tool for the correct aetiological diagnosis of ascites.

J Dhaka Med Coll. 2022; 31(1) : 120-124

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Published

2023-05-03

How to Cite

Khan, M. M. H. ., Rahman, F. ., Kamal, M. M. ., Momtaz, F. ., Patwary, M. I. ., & Islam, M. K. . (2023). Role of Serum Ascites Albumin Gradient In The Etiologic Diagnosis of Ascites. Journal of Dhaka Medical College, 31(1), 120–124. https://doi.org/10.3329/jdmc.v31i1.65486

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Original Articles