Distribution of Pruritus and Its Association With Serum Parathormone Level in Chronic Kidney Disease (Stage-5) Patients On Maintenance Hemodialysis

  • Rafiqul Hasan Assistant Professor, Dept. of Nephrology, Cox’s Bazar Medical College & Hospital
  • Md Nizamuddin Chowdhury Professor & Head, Dept. of Nephrology, Dhaka Medical College & Hospital
  • Md Nazrul Islam Associate Professor, Dept. of Nephrology, Dhaka Medical College & Hospital
  • Parvez Iftekher Ahmed Associate Professor, Dept. of Nephrology, Dhaka Medical College & Hospital
  • ASM Tanim Anwar Registrar, Dept. of Nephrology, Dhaka Medical College & Hospital
  • Mohammad Bellal Hossain Medical Officer, Dept. of Nephrology,Mymensingh Medical College & Hospital
  • Mohammad Shawkat Ali Medical Officer, Chittagong Medical College & Hospital
  • Md Saidur Rahman MD Thesis Part Student, Department of Nephrology, Dhaka Medical College & Hospital
Keywords: ESRD, parathyroid hormone, hemodialysis, pruritus

Abstract

Background: Pruritus is a common manifestation in patients on hemodialysis. The aim of this study is to determine the distribution of pruritus and evaluate the association between pruritus and serum parathormone levels in chronic kidney disease patients on maintenance haemodialysis.

Methods:This analytic, descriptive, cross-sectional study was performed over 191 patients of maintenance haemodialysis in 2014. Information related to the patients including age, gender, residence, pruritus was extracted from questionnaires. Serum levels of intact parathormone were measured & data were analyzed.

Results: 68% of the patients had pruritus. The Mean ± SD of serum parathormone was 53.25±7.96 pg/ml in patients with pruritus and 81.91±9.34 pg/ml in patients without pruritus. Our study showed that most patients with pruritus had normal serum parathormone levels and no significant association was found between pruritus and serum parathormone levels.

Conclusion: serum parathormone level may not play a role in uraemic pruritus in these patients.

J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 54-59

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Abstract
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Published
2020-03-03
How to Cite
Hasan, R., Chowdhury, M. N., Islam, M. N., Ahmed, P. I., Anwar, A. T., Hossain, M. B., Ali, M. S., & Rahman, M. S. (2020). Distribution of Pruritus and Its Association With Serum Parathormone Level in Chronic Kidney Disease (Stage-5) Patients On Maintenance Hemodialysis. Journal of Dhaka Medical College, 28(1), 54-59. https://doi.org/10.3329/jdmc.v28i1.45757
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Original Articles