An Unusual Cause of Generalized Swelling

  • Sabrina Shahrin FCPS Nephrology Trainee, Dhaka Medical College, Dhaka
  • Md Aminul Islam Transplant coordinator (Nephrology), Dhaka Medical College, Dhaka
  • Md Ehsan Uddin Khan Indoor Medical Officer (Nephrology), Dhaka
  • Parvez Iftekhar Ahmed Associate Professor (Nephrology), Dhaka Medical College, Dhaka
  • Md Nazrul Islam Associate Professor (Nephrology),Dhaka Medical College, Dhaka
  • Md Nizamuddin Chowdhury Professor (Nephrology), Dhaka Medical College, Dhaka

Abstract

Amyloidosis and multiple myeloma are included in the same spectrum of clonal plasma cell disorder. Amyloidosis can present with localized deposits or manifest as systemic disease involving multiple organs such as kidney, heart, intestine. Free Ig subunits ,mostly light chains secreted by a single clone of B cells, are the cause of the most frequent and severe amyloidosis affecting the kidney. The incidence of AL amyloidosis is nine per 1 million populations per year. Amyloid deposists are found in approximately 10% of all patients with myeloma and in 20% of those with pure light chain myeloma[1].Here we are reporting a case who initially presented with generalized swelling and subsequently found to have AL amyloidosis involving multiple organs due to multiple myeloma.

J Dhaka Medical College, Vol. 26, No.2, October, 2017, Page 173-177

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Abstract
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PDF
317
Published
2018-11-18
How to Cite
Shahrin, S., Islam, M. A., Khan, M. E., Ahmed, P., Islam, M. N., & Chowdhury, M. N. (2018). An Unusual Cause of Generalized Swelling. Journal of Dhaka Medical College, 26(2), 173-177. https://doi.org/10.3329/jdmc.v26i2.38839
Section
Case Reports