Comparison of Congenital Heart Disease between Neonates Born to Diabetic and Non-diabetic Mothers
Keywords:congenital heart disease, diabetic mother, gestational diabetes, echocardiogram
Background: Congenital heart disease (CHD) contributes about one-third of all major congenital anomalies in the world among the neonates, most common in infants of diabetic mothers but incidence is increasing all over the world due to establishing cardiac investigation facilities especially neonatal echocardiogram.
Materials & Methods: A hospital-based cross-sectional study was done in two private hospitals in Dhaka from July ’19 to June ’20. A total of 90 neonates were included from nursery and neonatal intensive care units of both hospitals who were requested for echocardiography as suspected CHD.
Results: In our study 52% mothers had diabetes mellitus (DM) during this conception and remains were normoglycemic. CHD present in 41.11% non-DM & DM mother’s offspring, there was no significant statistical difference among the groups (p=0.535). Gestational age and maternal coexisting diseases caused little impact on CHD in neonates (p <0.1). Regarding neonatal conditions only respiratory distress was significantly associated with CHD at p<0.05 level.
Conclusions: Researcher according to our study diabetes mellitus does not contribute to CHD in neonates. Researcher can focus on other maternal comorbidities and other factors like respiratory distress and cyanosis after birth, which may contribute to CHD in neonates.
J Bangladesh Coll Phys Surg 2023; 41: 27-32
How to Cite
Submission of a manuscript for publication implies the transfer of the copyright from the author to the publisher upon acceptance. Accepted manuscripts become the permanent property of the Journal of Bangladesh College of Physicians and Surgeons and may not be reproduced by any means in whole or in part without the written consent of the publisher.
No part of the materials published in this journal may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Reprints of any article in the Journal will be available from the publisher.