Intracerebral Haemorrhage with Choriocarcinoma in a Teenager - A Case Report
Intracerebral haemorrhage is one of the uncommon initial CNS manifestations of choriocarcinoma in reproductive age group women. Disease is usually diagnosed by history, clinical examinations and investigations like CT scan of brain and chest, MRI of brain, USG, X-ray chest P/A view and high level of â-hCG in serum and CSF. Overall prognosis of this disease is generally good (80-90% long term survival with chemotherapy and radiotherapy). But intracranial metastasis has poor prognosis which comprises 3-28% of choriocarcinoma. Most intracranial metastasis occurs late in the course of disease but 20% experiences as first sign. Our patient is a teenager girl presented with convulsion and loss of consciousness. CT scan of brain revealed hemorrhage in right fronto-parietal region with ventricular extension, X-ray chest P/A view shows metastasis in mid zone of right lung, USG shows invasion in posterior myometrium and high concentration of serum â-hCG (273400 mUI/ ml) confirmed our diagnosis. This case report describes that the conservative treatment with radiotherapy and chemotherapy gives good outcome of with metastasic intracerebral haemorrhage with choriocarcinoma is rewarding with farther radio and chemotherapy.
J Bangladesh Coll Phys Surg 2019; 37(3): 151-155
Submission of a manuscript for publication implies the transfer of the copyright from the author to the publisher upon acceptance. Accepted manuscripts become the permanent property of the Journal of Bangladesh College of Physicians and Surgeons and may not be reproduced by any means in whole or in part without the written consent of the publisher.
No part of the materials published in this journal may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Reprints of any article in the Journal will be available from the publisher.