Bombay Phenotype: Report of 2 Cases

Authors

  • TFA Dipta Associate Professor and Head, Department of Transfusion Medicine, BIRDEM and Ibrahim Medical College
  • KN Hossain Head, Blood Bank and Transfusion Services, ICDDR, B
  • A Khatun Associate Professor, Transfusion Medicine Department, BSMMU
  • M Rahman Medical officer, Transfusion Medicine Department, Square Hospitals Ltd.
  • AZ Hossain Associate Consultant, Department of Paediatric Surgery, Square Hospitals Ltd
  • A Wahed Associate Director, Medical Services, Square Hospitals Ltd.
  • N Shil Associate Professor, Transfusion Medicine Department, BSMMU

DOI:

https://doi.org/10.3329/jbcps.v29i4.11347

Keywords:

Bombay blood group, Bombay phenotype, ‘O’ blood group.

Abstract

Two cases of the rare blood group Bombay phenotype are discussed here. This rare blood group, Bombay (Oh) was first established by Bhende et al in Bombay (Mumbai), in 1952.In the ABO (ABH) blood group system, the O antigen represents the lack of A or B antigens; however it has the most amount of H antigen. If the H gene is absent, which is extremely rare, H substance can not be formed and subsequent A and B antigens can not also be formed. Absence of H gene results in the Bombay phenotype (Oh) 1-6, 7-13. Individuals with the Bombay phenotype develop anti-H antibodies. This is the reason that undetected Bombay individuals (typically typed as O individuals) will be cross match incompatible with O individuals. Bombay phenotype individuals can only receive blood from other Bombay individuals. In India, 1 in 10,000 has been found to have Bombay blood group. Where as, in Bangladesh till now only nine persons with Bombay (Oh) blood group have been formally reported by the Transfusion Medicine Department of Bangabandhu Sheikh Mujib Medical University (BSMMU). Using two cases we would like to discuss strategies to properly diagnose cases of Bombay phenotype in Bangladesh

 

DOI: http://dx.doi.org/10.3329/jbcps.v29i4.11347

 

J Bangladesh Coll Phys Surg 2011; 29: 241-243

 

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Published

2012-07-21

How to Cite

Dipta, T., Hossain, K., Khatun, A., Rahman, M., Hossain, A., Wahed, A., & Shil, N. (2012). Bombay Phenotype: Report of 2 Cases. Journal of Bangladesh College of Physicians and Surgeons, 29(4), 241–243. https://doi.org/10.3329/jbcps.v29i4.11347

Issue

Section

Case Reports