Spontaneous hypoglycemia: a review

  • Sultana Marufa Shefin Department of Endocrinology, BIRDEM General Hospital, Dhaka. Bangladesh
  • Nazmul Kabir Qureshi National Health Care Network, Uttara, Dhaka, Bangladesh
  • Ahmed Salam Mir Department of Endocrinology, Dhaka Central International Medical College, Dhaka, Bangladesh
  • Ahasnul Haq Amin Apollo Hospital Ltd., Dhaka, Bangladesh
  • Tareen Ahmed Health Education Department, BIRDEM General Hospital, Dhaka, Bangladesh
  • Faria Afsana Department of Endocrinology, BIRDEM General Hospital, Dhaka. Bangladesh
  • Md Shah Alam Comilla Diabetic Hospital, Comilla, Bangladesh
  • Farhana Akter Department of Endocrinology, Chittagong Medical College and Hospital. Chittagong, Bangladesh
  • Md Shah Emran Department of Endocrinology, MAG Osmani Medical College and Hospital, Sylhet, Bangladesh
  • Tanjina Hossain Department of Endocrinology, Green Life Medical College and Hospital, Dhaka, Bangladesh
  • Md Shahjamal Khan Department of Endocrinology, Enam Medical College and Hospital, Dhaka, Bangladesh
  • Marufa Mustari Department of Endocrinology, BSMMU, Dhaka, Bangladesh
  • Nusrat Sultana Department of Endocrinology, BSMMU, Dhaka, Bangladesh
  • Mohammad Saifuddin Abdul Malek Ukil Medical College and Hospital, Noakhali, Bangladesh
  • Sadiqa Tuqan Square Hospital Ltd., Dhaka, Bangladesh
  • Shahjada Selim Department of Endocrinology, BSMMU, Dhaka, Bangladesh
  • Samir Kumar Talukder Department of Endocrinology, Rangpur Medical College and Hospital. Rangpur, Bangladesh
  • Rafiq Uddin Department of Endocrinology, Chittagong Medical College and Hospital. Chittagong, Bangladesh
  • Md Feroz Amin Department of Endocrinology, BIRDEM General Hospital, Dhaka. Bangladesh
Keywords: Spontaneous hypoglycemia

Abstract

Spontaneous hypoglycemia is an important entity that may affect multiple organs. The differential diagnosis is broad in individuals with hypoglycemia in the absence of diabetes mellitus. Multiple etiologies may be present concurrently. Drugs, critical illnesses, hormone deficiencies, and non-islet cell tumors should be considered in those who are ill or taking medications. In apparently healthy individuals, endogenous hyperinsulinism due to insulinoma, functional β-cell disorders, or insulin autoimmune conditions are possible, as are accidental, surreptitious or factitious causes of hypoglycemia. Investigations should be guided by clinical scenario. Irrespective of the exact cause of the spontaneous hypoglycemia, treatment consists of correcting the glycemic state and preventing recurrence by alleviating underlying pathology. This review discusses the causes, diagnosis and management of spontaneous hypoglycemia.

IMC J Med Sci 2019; 13(1): 001

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Abstract
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PDF
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Published
2019-06-29
How to Cite
Shefin, S., Qureshi, N., Mir, A., Amin, A., Ahmed, T., Afsana, F., Alam, M. S., Akter, F., Emran, M. S., Hossain, T., Khan, M. S., Mustari, M., Sultana, N., Saifuddin, M., Tuqan, S., Selim, S., Talukder, S., Uddin, R., & Amin, M. F. (2019). Spontaneous hypoglycemia: a review. IMC Journal of Medical Science, 13(1), 001. https://doi.org/10.3329/imcjms.v13i1.42048
Section
Review Article