Synthesis of Ethyl 3,5-(Disubstituted Phenyl)-2-Isocyano-5-Oxopentanoate

Authors

  • Kawsari Akhter Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • Roksana Akter Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • S Mosaddeq Ahmed Department of Natural Science (Chemistry), American International University – Bangladesh (AIUB) 408/1 Kuratoli, Khilkhet, Dhaka-1229, Bangladesh
  • Md Ershad Halim Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

DOI:

https://doi.org/10.3329/dujs.v74i1.83479

Keywords:

Chalcones, ethyl cyanoacetate, sodium ethoxide, Michael addition

Abstract

The reactions between substituted chalcones 1a-d with ethyl cyanoacetate 2 were carried out in 1:1 molar ratio in the presence of sodium ethoxide as catalyst under refluxing condition to synthesize few chalcone derivatives, ethyl 3,5- (disubstituted phenyl)-2-isocyano-5-oxopentanoate, 3a-d. The structure of the compounds was determined by their chemical properties, UV, FT-IR, 1H-NMR, 13C-NMR, mass spectral data and elemental analyses.

Dhaka Univ. J. Sci. 74(1): 122-126, 2026 (January)

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Author Biographies

Kawsari Akhter, Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

 

 

Roksana Akter, Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

 

 

S Mosaddeq Ahmed, Department of Natural Science (Chemistry), American International University – Bangladesh (AIUB) 408/1 Kuratoli, Khilkhet, Dhaka-1229, Bangladesh

 

 

Md Ershad Halim, Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

 

 

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Published

2026-01-28

How to Cite

Akhter, K., Akter, R., Ahmed, S. M., & Halim, M. E. (2026). Synthesis of Ethyl 3,5-(Disubstituted Phenyl)-2-Isocyano-5-Oxopentanoate. Dhaka University Journal of Science, 74(1), 122–126. https://doi.org/10.3329/dujs.v74i1.83479

Issue

Vol. 74 No. 1 (2026)

Section

Articles