COVID-19 and Diabetes: Acknowledging the Bidirectional Link

Authors

  • Mohammad Rezaul Quader Associate Prof and head, Dept. of Biochemistry, Bangabandhu Sheikh Mujib Medical College, Faridpur.
  • Mohammad Jahidur Rahman Khan Assistant Professor, Dept. of Microbiology, Shaheed Suhrawardy Medical College, Dhaka.
  • Arifa Akram Assistant Professor, Dept. of Virology, National Institute of Laboratory Medicine and Referral Center, Dhaka.
  • Md Shahidul Islam Program Manager, Non Communicable Disease Control Program, Directorate General of Health Services (DGHS), Dhaka.
  • Nusrat Mannan Assistant Professor, Dept. of Microbiology, US-Bangla Medical College and Hospital, Narayanganj.
  • Md Sabir Hossain Professor, Dept. of Biochemistry and Molecular Biology, Jahangirnagar University, Dhaka
  • Nurul Karim Professor, Dept. of Biochemistry and Molecular Biology, Jahangirnagar University, Dhaka
  • Farha Matin Juliana Professor, Dept. of Biochemistry and Molecular Biology, Jahangirnagar University, Dhaka
  • Amirul Huda Bhuiyan Lecturer, Dhaka Medical College, Dhaka.
  • Paroma Deb Medical Officer, Mollapara Union Health Centre, Sunamganj.
  • Farhana Khatoon Assistant Professor, Dept. of Gynaecological Oncology, Bangabandhu Sheikh Mujib Medical University, Dhaka.
  • Farzana Mim Lab Consultant, Molecular Diagnostics Laboratory, Bangabandhu Sheikh Mujib Medical College, Faridpur.
  • Md Selim Reza Lab Consultant, Molecular Diagnostics Laboratory, Bangabandhu Sheikh Mujib Medical College, Faridpur.

DOI:

https://doi.org/10.3329/bsmmcj.v1i2.69349

Keywords:

COVID-19, Diabetes mellitus, Hyperglycemia, SARS-CoV-2, Cytokine storm

Abstract

COVID-19 and diabetes mellitus have a dynamic and bidirectional relationship. Diabetes is a risk factor for COVID-19. Diabetes mellitus is linked to hypercoagulability, inflammation, hyperglycemia, and other conditions (obesity, hypertension, cardiovascular disease, chronic kidney disease). Hyperglycemia may worsen SARS-CoV-2 infection. As a result of direct pancreatic damage caused by COVID-19, the stress response is triggered response to infection (including cytokine storm), including the use of hyperglycemic prescription medications such as corticosteroids for severe COVID-19, new-onset hyperglycemia and diabetes have been linked to the virus, as well as rapidly deteriorating blood glucose control in pre-existing diabetes. Insulin resistance and decreased b-cell secretion cause hyperglycemia. Challenges still remain in establishing the connection between COVID-19 and diabetes, whilst the
pandemic progresses.

Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):99-103

Abstract
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Published

2023-10-13

How to Cite

Quader, M. R. ., Khan, M. J. R. ., Akram, A. ., Islam, M. S. ., Mannan, N. ., Hossain, M. S., … Reza, . M. S. . (2023). COVID-19 and Diabetes: Acknowledging the Bidirectional Link. Bangabandhu Sheikh Mujib Medical College Journal, 1(2), 99–103. https://doi.org/10.3329/bsmmcj.v1i2.69349

Issue

Section

Review Article