Immune-Complex Mediated Crescentic Membranoproliferative Glomerulonephritis Presenting as Rapidly Progressive Renal Failure: A Case Report

Authors

  • Tahmida Tasnim Smrity Dhaka Medical College, Dhaka-1000, Bangladesh
  • Himel Saha Himu Dhaka Medical College, Dhaka-1000
  • Abdullah Al Mamun Dhaka Medical College, Dhaka-1000

DOI:

https://doi.org/10.3329/brej.v8i1.88172

Keywords:

Crescentic MPGN, Rapidly progressive glomerulonephritis, Immune-complex mediated glomerulonephritis, Cyclophosphamide, Glomerulonephritis, Renal biopsy

Abstract

Rapidly progressive glomerulonephritis represents a spectrum of diseases characterized by crescent formation in glomeruli and rapid decline in renal function. Membranoproliferative glomerulonephritis (MPGN) with crescentic transformation is rare and often presents with severe renal impairment. We report a case of a 40-years hypertensive woman who initially presented with acute kidney injury (AKI) and was treated as acute pyelonephritis. Due to rapid deterioration of renal function requiring hemodialysis, she was evaluated for RPGN. Renal biopsy revealed immune-complex mediated crescentic MPGN. Early aggressive immunosuppressive therapy resulted in significant renal recovery and dialysis independence.

Bang. Renal J. 2026; 8(1): 38-41

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Published

2026-03-10

How to Cite

Smrity, T. T., Himu, H. S., & Mamun, A. A. (2026). Immune-Complex Mediated Crescentic Membranoproliferative Glomerulonephritis Presenting as Rapidly Progressive Renal Failure: A Case Report. Bangladesh Renal Journal, 8(1), 38–41. https://doi.org/10.3329/brej.v8i1.88172

Issue

Vol. 8 No. 1 (2026)

Section

Case Report

License

Copyright (c) 2026 Bangladesh Renal Journal

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