Diagnosing of Small Vessel Vasculitis Might be a Challenge – A Rare Case Report

Authors

  • Md Abu Shahin Associate Professor, Department of Rheumatology Bangabandhu Sheikh Mujib Medical University (BSMMU), Shabagh, Dhaka, Bangladesh
  • Mohammad Mamun Khan Phase B Resident, Department of Rheumatology, BSMMU, Shabagh, Dhaka, Bangladesh
  • Swikriti Shrestha Phase B Resident, Department of Rheumatology, BSMMU, Shabagh, Dhaka, Bangladesh
  • Syed Jamil Abdal Medical Officer, Department of Rheumatology, BSMMU, Shabagh, Dhaka, Bangladesh
  • Md Ariful Islam Assistant Professor, Department of Rheumatology, BSMMU, Shabagh, Dhaka, Bangladesh
  • Minhaj Rahim Choudhury Professor, Department of Rheumatology, BSMMU, Shabagh, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bmj.v49i2.55819

Keywords:

Small vessel vasculitis, unclassi#ed purpura, neuropathy

Abstract

The term vasculitis refers to the inflammation of vessel walls. It may range in severity from a self-limited disorder in one single organ to a life-threatening disease due to multiple organ failure. Most patients with small vessel vasculitis present with constitutional symptoms like fever, malaise, weakness, fatigue and weight loss. To diagnose small vessel vasculitis, serology like ANCA, serum cryoglobulin and biopsy play an important role. Despite the serology and biopsy, diagnosing small vessel vasculitis occasionally remains challenging in resource constraint countries. Here we are reporting a case of a 26-year- old female who presented with purpura and neuropathy. The patient lacks clinical features like constitutional symptoms, renal involvement, upper airway involvement and her ANCA was negative. Depending on biopsy finding and skin and neurologic involvement, we diagnosed her as a case of small vessel vasculitis (unclassified). The patient improved with IV methylprednisolone followed by oral glucocorticoid treatment along with methotrexate. Although small vessel vasculitis has some typical features, diagnosis may often remain challenging even after biopsy.

Bangladesh Med J. 2020 May; 49(2) : 41-43

Downloads

Download data is not yet available.
Abstract
21
PDF
7

Downloads

Published

2020-03-23

How to Cite

Shahin, M. A. ., Khan, M. M. ., Shrestha, S. ., Abdal, S. J. ., Islam, M. A. ., & Choudhury, M. R. . (2020). Diagnosing of Small Vessel Vasculitis Might be a Challenge – A Rare Case Report. Bangladesh Medical Journal, 49(2), 41–43. https://doi.org/10.3329/bmj.v49i2.55819

Issue

Section

Case Reports