Gamma-glutamyl transferase is an indicator of gestational diabetes mellitus

Authors

  • Mousumi Ghosh Assistant Professor of Clinical Pathology, Department of Pathology, Monno Medical College & Hospital, Manikgonj, Dhaka
  • Debatosh Paul Associate Professor, Department of Clinical Pathology, BSMMU, Dhaka
  • Md Saiful Islam Assistant Professor, Department of Clinical Pathology , BSMMU, Dhaka
  • Gopal Chandra Ghosh Senior House Officer, Department of Cardiothoracic Surgery, United Hospital, Gulshan, Dhaka
  • Mohammad Monzurul Alam Bhuiyan Clinical Pathologist, Department of Clinical Pathology, Sir Salimullah Medical College & Mitford Hospital, Dhaka
  • Sharmin Akter Assistant Registrar, Department of Obstetrics & Gynaecology, Institute of Child & Mother Health, Matuail, Dhaka.
  • Tuhin Sultana Associate Professor, Department of Clinical Pathology, BSMMU, Dhaka
  • Md Quddusur Rahman Chairman, Department of Clinical Pathology, BSMMU, Dhaka
  • AN Nashimuddin Ahmed Professor, Department of Clinical Pathology, Bangabandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/bmj.v44i3.27375

Keywords:

Gamma-glutamyl transferase(GGT), gestational diabetes mellitus(GDM), pregnancy, liver enzyme

Abstract

Increased gamma-glutamyl transferase (GGT) is associated with gestational diabetes mellitus (GDM) and type 2 diabetes mellitus in pregnant women. This cross sectional study was conducted in the Department of Clinical Pathology in collaboration with Department of Obstetrics and Gynecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from March 2014 to February 2015 to assess the GGT as an indicator of GDM. Total 66 pregnant women were enrolled in this study in the Department of Obstetrics and Gynecology, BSMMU. Total 33 cases were considered as Group I (GDM) and 33 controls were Group II (normal healthy pregnant women). Two ml of blood was collected in plain test tube from each patient. Gestational diabetes mellitus were diagnosed by FBS and 2hr after 75g glucose in this study as cases. Normal healthy pregnant women was included in this study as control. GGT was higher in GDM group compared to normal healthy pregnant women (30.60±7.78 vs. 16.45±4.97, p<0.001). So, with the help of GGT we can take preventive measure and precaution to reduce the risk of GDM in pregnant women.

Bangladesh Med J. 2015 Sep; 44 (3): 152-156

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Author Biography

Mousumi Ghosh, Assistant Professor of Clinical Pathology, Department of Pathology, Monno Medical College & Hospital, Manikgonj, Dhaka



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Published

2016-04-17

How to Cite

Ghosh, M., Paul, D., Islam, M. S., Ghosh, G. C., Bhuiyan, M. M. A., Akter, S., Sultana, T., Rahman, M. Q., & Ahmed, A. N. (2016). Gamma-glutamyl transferase is an indicator of gestational diabetes mellitus. Bangladesh Medical Journal, 44(3), 152–156. https://doi.org/10.3329/bmj.v44i3.27375

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Original Articles