In vitro antioxidant and antinociceptive potentialities of methanolic extract of Litsea glutinosa

  • NN Rumzhum Laboratory of Pharmacognosy and Pharmacology, Department of Pharmacy, Stamford University, Dhaka-1217
  • MM Rahman Laboratory of Pharmacognosy and Pharmacology, Department of Pharmacy, Stamford University, Dhaka-1217
  • AA Sharukh Laboratory of Pharmacognosy and Pharmacology, Department of Pharmacy, Stamford University, Dhaka-1217
  • SA Chowdhury Laboratory of Pharmacognosy and Pharmacology, Department of Pharmacy, Stamford University, Dhaka-1217
  • MN Pervin Laboratory of Pharmacognosy and Pharmacology, Department of Pharmacy, Stamford University, Dhaka-1217
Keywords: Litsea glutinosa, Lauraceae, Antioxidant, Antinociceptive, Swiss albino mice

Abstract

The methanolic extract of Litsea glutinosa (Lauraceae) was evaluated for in vitro antioxidant activity by determination of hydrogen peroxide scavenging activity, total antioxidant capacity, assay of nitric oxide scavenging activity and reducing power test and in vivo antinociceptive effect in acetic acid induced writhing model in swiss albino mice. The results revealed the presence of pronounced antioxidant property as compared with ascorbic acid used as standard and a dose-dependent (250 and 500 mg/kg) analgesic effect. The antioxidant and antinociceptive properties observed seem to be in good accordance with the traditional uses of Litsea glutinosa.

Bangladesh J. Sci. Ind. Res. 47(4), 401-406, 2012

DOI: http://dx.doi.org/10.3329/bjsir.v47i4.14069

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Abstract
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Published
2013-03-06
How to Cite
Rumzhum, N., Rahman, M., Sharukh, A., Chowdhury, S., & Pervin, M. (2013). In vitro antioxidant and antinociceptive potentialities of methanolic extract of Litsea glutinosa. Bangladesh Journal of Scientific and Industrial Research, 47(4), 401-406. https://doi.org/10.3329/bjsir.v47i4.14069
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Articles