Antimicrobial Activity of Akanda (<i>Calotropis gigantea</i> L.) on Some Pathogenic Bacteria.

Authors

  • M Ashraful Alam Department of Biochemistry and Molecular Biology, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh
  • M Rowshanul Habib Department of Biochemistry and Molecular Biology, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh
  • Rarjana Nikkon Department of Biochemistry and Molecular Biology, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh
  • Matiar Rahman Department of Biochemistry and Molecular Biology, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh
  • M Rezaul Karim Department of Biochemistry and Molecular Biology, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh

DOI:

https://doi.org/10.3329/bjsir.v43i3.1156

Keywords:

Methanol extract, Akonda (Calotropis gigantea), Petroleum ether fraction, Chloroform fraction and Ethyl acetate fraction.

Abstract

The antibacterial activity of methanol extract from the root bark of Akanda (Calotropis gigantea L.) and its petroleum ether, chloroform and ethyl acetate fractions were investigated. Both of methanol extract and its chloroform fraction showed activity against Sarcina lutea, Bacillus megaterium and Pseudomonas aeruginosa. Petroleum ether fraction showed activity against Bacillus subtilis and Shigella sonnei whereas ethyl acetate fraction showed activity against Pseudomonas aeruginosa and Escherichia coli at 20ìg/disc, 30ìg/disc and 40ìg/disc doses. Among the tested materials, methanol extract and its chloroform fraction showed comparatively better results. Minimum inhibitory concentration (MIC) for methanol extract and each fraction were also determined by serial dilution technique.

Keywords: Methanol extract, Akonda (Calotropis gigantea), Petroleum ether fraction, Chloroform fraction and Ethyl acetate fraction.   

DOI = 10.3329/bjsir.v43i3.1156

Bangladesh J. Sci. Ind. Res. 43(3), 397-404, 2008

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How to Cite

Alam, M. A., Habib, M. R., Nikkon, R., Rahman, M., & Karim, M. R. (2008). Antimicrobial Activity of Akanda (<i>Calotropis gigantea</i> L.) on Some Pathogenic Bacteria. Bangladesh Journal of Scientific and Industrial Research, 43(3), 397–404. https://doi.org/10.3329/bjsir.v43i3.1156

Issue

Section

Short Communications