Studies on locally available three anti-diabetic herbal medicines

  • Mohammad Shoeb Department of Chemistry, University of Dhaka, Dhaka 1000
  • Naznin Nahar Department of Chemistry, University of Dhaka, Dhaka 1000
  • Farouq Ahmed Department of Chemistry, University of Dhaka, Dhaka 1000
  • M. Mosihuzzaman Department of Chemistry, University of Dhaka, Dhaka 1000
  • Nilufar Nahar Department of Chemistry, University of Dhaka, Dhaka 1000
Keywords: Benzoic acid, Herbal medicine, Oleic acid

Abstract

Herbal medicines are being used for the treatment of different diseases for centuries. Sustainable development of herbal medicines need the study of their safety, efficacy and standardization are essential. Two commercially available herbal medicines i.e., Ziabetes (dolabi) and Jambadayrist, and a folkloric medicine prepared from four plant materials by a local practitioners were investigated for their chemical compositions.  Four compounds were isolated from the extracts of these medicines by silica gel column chromatography. Oleic acid and p-hydroxycinnamic acid were isolated from the aqueous 80%ethanol extract of the folkloric medicine whereas benzoic acid was found to be present in Ziabetes and Jambadayrist. The present investigation revealed that excessive amount of benzoic acid (or sodium benzoate) is being added as preservative in commercial herbal medicines.

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Author Biographies

Mohammad Shoeb, Department of Chemistry, University of Dhaka, Dhaka 1000

Associate Professor

M. Mosihuzzaman, Department of Chemistry, University of Dhaka, Dhaka 1000
Professor
Nilufar Nahar, Department of Chemistry, University of Dhaka, Dhaka 1000
Professor

References

De Smet PAGM. Herbal medicine in Europe: Relaxing regulatory standards. New Engl J Med. 2005; 54: 801-40.

Fisher P, Ward A. Complementary medicine in Europe. Brit Med J. 1994; 309: 107-11.

Haddock EA, Gupta RK, Al-Shafi SMK, layden K, Haslam E, Magnolato D. The metabolism of gallic acid and hexahydroxydiphenic acid in plants: biogenetic and molecular taxonomic considerations. Phytochemistry 1982; 21: 1049-62.

Mosihuzzaman M, Choudhary MI. Protocols on safety, efficacy, standardization, and documentation of herbal medicine. Pure Appl Chem. 2008; 80: 2195-230.

Newman DJ, Cragg GM, Snader KM. The influence of natural products upon drug discovery. Nat Prod Rep. 2000; 17: 215-34.

Shoeb M, Begum S, Mamun MIR, Nahar N, Study of an endophytic fungus from Aquilaria malaccensis Lamk. J Bangladesh Chem Soc. 2010; 23: 101-07.

Shoeb M, MacManus S M, Jaspars M, Trevidadu J, Nahar L, Kong-Thoo-Lin P, Sarker SD. Montamine a unique dimeric indole alkaloid, from the seeds of Centaurea montana (Asteraceae), and its in vitro cytotoxic activity against the CaCo2 colon cancer cells. Tetrahedron 2006; 62: 11172-77.

TDR. Operational guidance: Information needed to support clinical trials of herbal products. UNICEF/UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases (TDR). 2005.

Ugar G, Chris S. n-3 Omega fatty acids: A review of current knowledge. Inter J Food Sci Tech. 2010; 45: 417-36.

Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care. 2004; 27: 1047-53.

Published
2011-12-22
How to Cite
Shoeb, M., N. Nahar, F. Ahmed, M. Mosihuzzaman, and N. Nahar. “Studies on Locally Available Three Anti-Diabetic Herbal Medicines”. Bangladesh Journal of Pharmacology, Vol. 6, no. 2, Dec. 2011, pp. 124-7, doi:10.3329/bjp.v6i2.9216.
Section
Research Articles