Wound healing effect of different extracts of Centaurea pterocaula

  • Barış Ötün Bitlis Eren University Hizan Vocational School, Bitlis, Turkey
  • Ufuk Mercan Yücel Van Yüzüncü Yil Üniversity, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Van, Turkey https://orcid.org/0000-0001-8256-7868
Keywords: Centaurea pterocaula, Skin wound creation, Wound healing

Abstract

In this study, the effect of different extracts of Centaurea pterocaula were evaluated on 6 mm wound created by punch biopsy on the rat back. The leaves of the plant were powdered and extracted with distilled water, methanol, n-hexane and ethyl acetate. Extracts were obtained in the form of pomade with vaseline and applied topically to the wounds. The wound measurements performed on day 0, 2, 4, 6, 8, 10 and 12 and the histo-pathological examination performed on day 12. The n-hexane extract had an accelerating effect on wound healing and made a positive contribution to the healing process. In conclusion, C. pterocaula has a promising future for new drug development studies by its wound healing property.

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Published
2019-01-14
How to Cite
Ötün, B., and U. Yücel. “Wound Healing Effect of Different Extracts of Centaurea Pterocaula”. Bangladesh Journal of Pharmacology, Vol. 14, no. 1, Jan. 2019, pp. 9-16, doi:10.3329/bjp.v14i1.38444.
Section
Research Articles