Taxithelium napalense acts against free radicals and diabetes mellitus

Authors

DOI:

https://doi.org/10.3329/bjp.v12i2.31764

Keywords:

Antidiabetic, Anti-oxidant, Free radical, Taxithelium napalense

Abstract

In this work, Taxithelium nepalense ethanolic extract and its fractions were evaluated for the antidiabetic activity in rat based on phytochemical and free radical scavenging properties. The ethanolic extract, fraction IV and V significantly attenuated the blood glucose levels at 600, 200 and 200 mg/kg with 50.0, 33.5 and 42.0% inhibition respectively. The histopathological studies were manifesting the recuperation of damaged cells in liver and pancreas tissues. The outcomes of the present work affirm that the T. nepalense has a potency to plummet the overproduction of free radicals and blood glucose levels in the diabetic-induced rat.

Video Clip of Methodology:

Induction of diabetes:  1 min 50 sec   Full Screen   Alternate

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Author Biographies

Kishore Naidu Killari, Andhra University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh

Research Scholar

Vedula Girija Sastry, Andhra University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh

Professor

Additional Files

Published

2017-06-16

How to Cite

Tatipamula, V. B., K. N. Killari, A. Ketha, and V. G. Sastry. “Taxithelium Napalense Acts Against Free Radicals and Diabetes Mellitus”. Bangladesh Journal of Pharmacology, vol. 12, no. 2, June 2017, pp. 197-03, doi:10.3329/bjp.v12i2.31764.

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Section

Research Articles