Pattern of skin bacteria in palmar arsenical keratosis
Keywords:Arsenical keratosis, Bacteria, Palm, Skin
The aim of the present study was to examine the involvement of skin bacteria in the pathogenesis of keratosis. Skin swab of five different sites (palm, dorsum of the hand, chest, axilla and alar crease) from arsenic unexposed volunteer (n = 15), arsenic exposed (n = 15) and arsenicosis patients (n= 20) were collected for bacterial culture. The skin of arsenic unexposed volunteers contained Staphylococcus epidermidis and Bacillus spp. Chronic exposure to high concentration of arsenic through drinking water altered the skin bacterial pattern. The growth of Pseudomonas spp. increased in different sites of the skin. But in patient of arsenicosis, the skin of the palm shows the growth of Enterobacter spp.
Aly R, Maibach HI. Aerobic microbial flora of intertrigenous skin. Appl Environ Microbil. 1977; 33: 97-100.
Baker H, Kligman AM. Measurement of transepidermal water loss by electrical hygrometry: Instrumentation and responses to physical and chemical insults. Arch Dermatol. 1967; 96: 441-52.
Bhuiyan HA, Tshering K, Misbahuddin M. Estimation of arsenic in nail using silver diethyldithiocarbamate method. Bangladesh J Pharmacol. 2015; 10: 513-17.
Caussy D. A field guide for detection, management and surveillance of arsenicosis cases. New Delhi, WHO Regional Office for South-East Asia, 2005.
Grice EA, Kong HH, Conlan S, et al. Topographical and temporal diversity of the human skin microbiome. Science 2009; 324: 1190-92.
Grice EZ, Segre JA. The skin microbiome. Nat Rev Microbiol. 2011; 9: 244-53.
Jyoti A, Bonny TS, Hossain MA. Arsenic poisoning alters the composition of skin microbial flora of human. Res J Microbiol. 2011; 6: 524-33.
Kligman AM. The bacteriology of normal skin. In: Skin bacteria and their role. Maibach HI, Hildick-Smith G (ed.). New York, McGraw-Hill, 1965, pp 13-31.
Misbahuddin M. Arsenicosis: A global issue. New York, Science Publishing Group, 2015, pp 1-204.
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