Phytochemical studies and antibacterial activity of the aerial parts of Physospermum verticillatum

Authors

  • Ibtissem Boulacel Valorization of Natural Resources, Bioactive Molecules and Biological Analysis Unit, Department of Chemistry, University of Mentouri Constantine1, Constantine 25000
  • Lakhdar Djarri Valorization of Natural Resources, Bioactive Molecules and Biological Analysis Unit, Department of Chemistry, University of Mentouri Constantine1, Constantine 25000
  • Salima Azzouzi University of Çank?r? Karatekin, Faculty of Science, Department of Chemistry, Ballica Campus, Çank?r? 18100
  • Kamel Medjroubi University of Çank?r? Karatekin, Faculty of Science, Department of Chemistry, Ballica Campus, Çank?r? 18100
  • Ibrahim Demirtas University of Çank?r? Karatekin, Faculty of Science, Department of Chemistry, Ballica Campus, Çank?r? 18100
  • Hocine Laouer Laboratory of Natural Biological Resources Valorization, Faculty of Sciences, University of Setif, Setif 19000
  • Salah Akkal Valorization of Natural Resources, Bioactive Molecules and Biological Analysis Unit, Department of Chemistry, University of Mentouri Constantine1, Constantine 25000 http://orcid.org/0000-0002-4999-5673

DOI:

https://doi.org/10.3329/bjp.v12i2.29668

Keywords:

Antibacterial, Physospermum verticillatum

Abstract

In this study, we focused on the isolation and identification of the main compounds, triterpene, sterol, phenolic and fatty acid from the aerial parts of Physospermum verticillatum, which has not been previously reported. Dichloromethane, ethyl acetate and n-butanol extracts led to the isolation  of ß-amyrin (1), 3,11-dihydroxy-12-oleanene (2), pentadecanoic acid (3), spina-sterol (4), spinasterol-3-O-ß-D-glucopyranoside (5) and saikochromic acid (6). These compounds were determined by means of the combined systems with high resolution tandem mass spectrometry (HPLC-TOF/MS), 1D NMR (1H NMR, 13C NMR) and 2D NMR(COSY, HSQC and HMBC). Further, the extracts demonstrated significant antibacterial activity.

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Published

2017-04-05

How to Cite

Boulacel, I., L. Djarri, S. Azzouzi, K. Medjroubi, I. Demirtas, H. Laouer, and S. Akkal. “Phytochemical Studies and Antibacterial Activity of the Aerial Parts of Physospermum Verticillatum”. Bangladesh Journal of Pharmacology, vol. 12, no. 2, Apr. 2017, pp. 107-12, doi:10.3329/bjp.v12i2.29668.

Issue

Vol. 12 No. 2 (2017)

Section

Research Articles

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