Antitoxin activity of Mimosa pudica root extracts against Naja naja and Bangarus caerulus venoms

  • Subramani Meenatchisundaram Department of Microbiology, Nehru Arts and Science College, Coimbatore
  • Selvin Priyagrace Department of Microbiology, Nehru Arts and Science College, Coimbatore
  • Ramasamy Vijayaraghavan Department of Microbiology, Nehru Arts and Science College, Coimbatore
  • Ambikapathi Velmurugan Department of Microbiology, Nehru Arts and Science College, Coimbatore
  • Govindarajan Parameswari Department of Microbiology, PSG College of Arts and Science, Coimbatore
  • Antonysamy Michael Department of Microbiology, PSG College of Arts and Science, Coimbatore
Keywords: Bangarus caerulus, Edema, Mimosa pudica, Naja naja, Venom

Abstract

Aqueous extract of dried roots of Mimosa pudica was tested for inhibitory activity on lethality, phospholipase activity, edema forming activity, fibrinolytic activity and hemorrhagic activity of Naja naja and Bangarus caerulus venoms. The aqueous extract displayed a significant inhibitory effect on the lethality, phospholipase activity, edema forming activity, fibrinolytic activity and hemorrhagic activity. About 0.14 mg and 0.16 mg of M. pudica extracts were able to completely neutralize the lethal activity of 2LD50 of Naja naja and Bangarus caerulus venoms respectively. The present finding suggests that aqueous extract of M. pudica root possesses compounds, which inhibit the activity of Naja naja and Bangarus caerulus venoms.

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Published
2009-05-03
How to Cite
Meenatchisundaram, S., S. Priyagrace, R. Vijayaraghavan, A. Velmurugan, G. Parameswari, and A. Michael. “Antitoxin Activity of Mimosa Pudica Root Extracts Against Naja Naja and Bangarus Caerulus Venoms”. Bangladesh Journal of Pharmacology, Vol. 4, no. 2, May 2009, pp. 105-9, doi:10.3329/bjp.v4i2.2276.
Section
Research Articles