Anti-acne activity of Casuarina equisetifolia bark extract: A randomized clinical trial


  • Yousra Shafiq Department of Pharmaceutics, Faculty of Pharmacy, University of Karachi
  • Baqir Shyum Naqvi Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, Karachi
  • Ghazala H. Rizwani Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi
  • Muhammed Usman Nigehban Pharmacy, Dhoraji, Karachi
  • Barkat Ali Shah Model Skin Laser Clinic, Karachi
  • Muhammad Aslam Department of Pharmacology, Faculty of Pharmacy, University of Karachi
  • Bushra Hina Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi



Anti-acne, Acne vulgaris, Casuarina equisetifolia, Benzoyl peroxide


The objective of this study was to evaluate the clinical efficacy of Casuarina equisetifolia bark extract (5% cream) in comparison with benzoyl peroxide as the standard drug for acne vulgaris. After exclusion, fifty patients were included in the study (n=50) with age group distribution between 17-34 years of age. Patients were distributed into Group 1 (5% cream) and Group 2 (benzoyl peroxide), and were advised to apply the herbal cream twice a day topically. The clinical efficacy of the herbal cream and severity of acne vulgaris was assessed by Cook's acne grading scale. Results revealed that there was no significant difference found in both test and standard control groups. Further, remarkable improvement was found in acne grading in the test group.


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How to Cite

Shafiq, Y., B. S. Naqvi, G. H. Rizwani, M. Usman, B. A. Shah, M. Aslam, and B. Hina. “Anti-Acne Activity of Casuarina Equisetifolia Bark Extract: A Randomized Clinical Trial”. Bangladesh Journal of Pharmacology, vol. 9, no. 3, Aug. 2014, pp. 337-41, doi:10.3329/bjp.v9i3.19342.



Clinical Trial