In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes

Authors

  • Afide Öcal Bozok University, Science Institute, Department of Biology, Yozgat
  • Halil Erhan Eroğlu Bozok University, Faculty of Science and Art, Department of Biology, Yozgat

DOI:

https://doi.org/10.3329/bjp.v7i1.10119

Keywords:

Hypericum heterophyllum, Cytogenetic, Mitotic index, Replication index

Abstract

Hypericum species have been used in traditional medicine in Turkey for thousands of years. In order to determine the cytogenetic effects of Hypericum heterophyllum, human lymphocytes were incubated with the aqueous extracts. Mitotic index frequencies and replication index values were increased with increasing extract concentrations of H. heterophyllum. The results indicate the cytotoxic effects as well as proliferative effects and suggest that the extracts of the compounds exhibit cytotoxic properties as well as mitotic and proliferative properties.

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References

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Published

2012-04-22

How to Cite

Öcal, A., and H. E. Eroğlu. “In Vitro Cytogenetic Effects of Hypericum Heterophyllum in Human Peripheral Blood Lymphocytes”. Bangladesh Journal of Pharmacology, vol. 7, no. 1, Apr. 2012, pp. 36-41, doi:10.3329/bjp.v7i1.10119.

Issue

Section

Research Articles