Microbiological Trends and Antibiotic Sensitivity in Chronic Otitis Media in a tertiary care Hospital, Dhaka
Keywords:
Pseudomonas aeruginosa, Staphylococcus aureus, Chronic Otitis Media, Antibiotic sensitivity.Abstract
Background:: Chronic otitis media (COM) is a persistent ear infection characterized by the ongoing discharge of pus from the middle ear, often leading to hearing loss and other complications. The condition is commonly caused by bacterial and fungal pathogens, with Pseudomonas aeruginosa and Staphylococcus aureus being the predominant microorganisms identified in many cases. This study aims to examine the microbiological and antibiotic resistance profiles of COM.
Methods: This cross-sectional study was conducted to evaluate the microbiological profile and antibiotic resistance patterns in patients with chronic otitis media (COM). The study was carried out from June 2023 to June 2024, in the Department of Otolaryngology- Head & Neck Surgery and Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University, Dhaka. Statistical analysis was performed using SPSS (Statistical Package for Social Sciences) version 25.0.
Results: Pseudomonas aeruginosa and Staphylococcus aureus were the most common pathogens, each accounting for 33.3% of isolates. The majority of patients had a single microbial isolate (70.9%). Antibiotic sensitivity testing revealed that gentamicin was the most effective topical antibiotic (82.6% sensitivity), followed by neomycin and chloramphenicol. Systemic antibiotics showed varied resistance, with P. aeruginosa being most sensitive to piperacillin-tazobactam and S. aureus being fully sensitive to vancomycin. Coagulase-negative staphylococci showed significant resistance to oxacillin but remained sensitive to vancomycin and linezolid.
Conclusion: Pseudomonas aeruginosa and Staphylococcus aureus as the predominant pathogens in chronic otitis media (COM), with concerning levels of antibiotic resistance. While gentamicin remains the most effective topical antibiotic, the rising resistance to commonly used systemic antibiotics necessitates culture-based treatment strategies.
Bangladesh J Otorhinolaryngol 2026; 32(1): 31-38
0
Downloads
Published
How to Cite
Issue
Section
License
Manuscripts submitted for publication in the Bangladesh Journal of Otorhinolaryngology must not have been previously submitted or published. Accepted papers become the permanent property of the Bangladesh Journal of Otorhinolaryngology. By submitting a manuscript, the authors(s) agree that copyrights for their articles are automatically transferred to Bangladesh Journal of Otorhinolaryngology, if and when the articles are accepted for publication.
The use, in this journal, of registered trade names, trade marks, etc. without special acknowledgement does not imply that such names, as defined by the relevant protection laws, be regarded as unprotected, and, thus, free for general use.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
