Evaluation of Post-Hemithyroidectomy hypothyroidism

  • SM Abdul Awual Assistant Professor (ENT), Sir Salimullah Medical College, Dhaka, Bangladesh
  • Syeda Marufa Hasan Assistant Professor (Biochemistry), National Institute of Laboratory Medicine and Referral Center, Dhaka, Bangladesh
  • Suhel Al Muzahid Reza Assistant Professor (Urology), Sheikh Hasina Medical College, Tangail, Bangladesh
  • Md Shahriar Islam Registrar (ENT), Sir Salimullah Medical College Mitford Hospital, Dhaka, Bangladesh
  • Utpaul Kumar Sarkar Assistant Registrar (ENT), Sir Salimullah Medical College Mitford Hospital, Dhaka, Bangladesh
  • Md Abul Kashem Assistant Registrar (ENT), Sir Salimullah Medical College Mitford Hospital, Dhaka, Bangladesh
Keywords: Hemithyroidectomy, Hypothyroidism, Risk factors

Abstract

Objective: To evaluate the incidence of post-hemithyroidectomy hypothyroidism and identify possible risk factors that indicates which patients require thyroid function monitoring after surgery.

Methods: A prospective study of patients with benign, non-toxic thyroid disease undergoing hemithyroidectomy between January 2017 and July 2019 in the Department of Otolaryngology and Head-Neck Surgery, Sir Salimullah Medical College Mitford Hospital, Dhaka. All patients were in euthyroid state preoperatively.Thyroid specimens were examined for pathological diagnosis and thyroid function was evaluated again six weeks after surgery.

Results: All had normal preoperative thyroid function. Six weeks after surgery, 10 (22.22%) of the cases developed hypothyroidism (6.66% overt or symptomatic hypothyroidism and 15.56% subclinical hypothyroidism). The mean preoperative TSH level was significantly higher in the hypothyroid group than in the euthyroid group (2.1±1.1 vs 1.3±0.7mIU/L, p<0.01).Seven of patients with preoperative thyroid stimulating hormone (TSH) level more than or equal to 2 mIU/L developed hypothyroidism in comparison to only 3 of those with preoperative TSH <2 mIU/L (odds ratio 11.3).

Conclusion: Ten (22.22%) patients in the present study developed hypothyroidism after hemithyroidectomy. Preoperative TSH more than or equal 2 mIU/L, elevation of thyroid antibodies and thyroiditiswarrant post-operative close TSH monitoring. Awareness of such risk factors for post-operative hypothyroidism would improve patients care and reduce complications.

Bangladesh J Otorhinolaryngol; October 2020; 26(2): 95-101

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Abstract
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Published
2020-12-09
How to Cite
Awual, S., Hasan, S., Reza, S. A., Islam, M. S., Sarkar, U., & Kashem, M. A. (2020). Evaluation of Post-Hemithyroidectomy hypothyroidism. Bangladesh Journal of Otorhinolaryngology, 26(2), 95-101. https://doi.org/10.3329/bjo.v26i2.50608
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Original Articles