Bilateral Langerhans Cells Histiocytosis in the Temporal Bone: A case report

  • Kanu Lal Saha Associate Professor, Department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Bishnu Pada Dey Professor, Department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Md Abul Hasnat Joarder Assistant Registrar, Department of ENT, Shaheed Tajuddin Ahmed Medical College, Gazipur,Bangladesh
  • Mohammad Anamul Haque Associate Professor, Department of Radiology and Imaging, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Bishwajit Bhowmik Assistant Professor, Department of Pathology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Keywords: Histiocytosis, blood stained discharge

Abstract

Langerhans cells histiocytosis (LCH) or histiocytosis-X is a rare group diseases that includes three overlapping diseases of Hand-Schuller-Christian disease (HSC), Letterer-Siwe disease (LS)and Eosinophilic granuloma(EG). It results from clonal proliferation of histiocytes having similar morphology and immunophenotype to Langerhans cells in skin and mucosa Though head and neck manifestation is common, isolated simultaneous bilateral temporal bone Langerhans Cell Histiocytosis is an extremely rare presentation. Having same otological menifestations, high resolution CT scan is advocated for early identification and differentiation of LCH from other common conditions such as mastoidits,otitis externa ,chronic suppurative otitis media. Diagnosis of LCH is confirmed by biopsy and immunohistochemical staining of S-100 protein and or CD1a antigen. Chemotherapy is main mode of treatment.The prognosis is worse when presenting age of children is younger than 2 years.

Bangladesh J Otorhinolaryngol; April 2020; 26(1): 68-72

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Abstract
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PDF
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Published
2020-07-01
How to Cite
Saha, K. L., Dey, B. P., Joarder, M. A. H., Haque, M. A., & Bhowmik, B. (2020). Bilateral Langerhans Cells Histiocytosis in the Temporal Bone: A case report. Bangladesh Journal of Otorhinolaryngology, 26(1), 68-72. https://doi.org/10.3329/bjo.v26i1.47956
Section
Case Reports