Primary Amyloidosis of Larynx – A Case Report

  • Kanu Lal Saha Assistant Professor, Department of Otolaryngology-Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Pran Gopal Datta Professor, Department of Otolaryngology- Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Utpal Kumar Dutta Assistant Professor, Department of Otolaryngology-Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • ATM Khalilur Rahman Professor, Department of Cardiac Aneathesia, National Heart Foundation Hospital and Research Institute, Dhaka
  • Shabnam Akhter Associate Professor, Department of Pathology, Bangabandhu Sheikh Mujib Medical University, Dhaka
Keywords: Amyloidosis, larynxl tuberculosis, CO2 laserIntroduction

Abstract

Amyloidosis is an idiopathic benign disorder in which extracellular proteinaceous material deposits in variety of organs leading to tissue damage and functional problem of that organ. Besides larynx being the commonest site, amyloidosis is found in other head neck sites such as salivary glands, oral cavity, pharynx, nasopharynx, sinonasal cavity, trachea, bronchi, lungs & lymph node. This is a report of a 40 year old man admitted in the departement of Otolaryngology-Head and Neck Surgery, BSMMU, Dhaka, Bangladesh, in 2014, presented with history of hoarseness of voice and polypoidal swelling involving left vocal cord, ventricle and vestibular fold. Initially he was treated with antitubercular chemotherapy as direct laryngoscopic biopsy reported tuberculosis. As symptoms did not subside repeat direct endoscopic biopsy was done when histopathological examination confirmed the diagnosis of amyloidosis. MRI shows transglottic involvement of lesion which appears more extensive than endoscopic findings. Regular follow-up is necessary to assess accurately the disease progression, using conservative clinical management to preserve laryngeal function.

DOI: http://dx.doi.org/10.3329/bjo.v20i2.22026

Bangladesh J Otorhinolaryngol; October 2014; 20(2): 98-101

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Abstract
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PDF
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Published
2015-02-09
How to Cite
Saha, K., Datta, P., Dutta, U., Rahman, A., & Akhter, S. (2015). Primary Amyloidosis of Larynx – A Case Report. Bangladesh Journal of Otorhinolaryngology, 20(2), 93-97. https://doi.org/10.3329/bjo.v20i2.22026
Section
Case Reports