Frequency of Malignancy in Multinodular Goitre
Keywords:Malignancy, Multinodular Goiter
Objectives: To determine the frequency of thyroid carcinoma in clinically or sonogragraphically multinodular goitre in patients undergoing thyroidectomy
Setting: This is a cross sectional study was carried out at the Department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University during the period from January 2012 to June 2012.
Methods: This study includes all the patients admitted in Otolaryngology and Head-Neck surgery department of Bangabandhu Sheikh Mujib Medical University having diagnosis of multinodular goitre & underwent thyroidectomy. All patients with non-toxic multinodular goitre (clinically or sonographically) irrespective of age , sex was be included .
Results: Out of 50 patients, 41 patients (82%) were female, and 9 patients (18%) were male with a female to male ratio 4.5: 1. This shows female preponderance of multinodular goitre. Out of 50 patients, 5 patients had histologicaly proven thyroid malignancy (4 females and 1 male). In this study overall incidence of carcinoma in multinodular goitre was 10% and female to male ratio 4:1 with the incidence in female was 9.75% and in male 11.11. The incidence of malignancy under 21 years was 50% and above 21 years was 8.33%. Regarding the types of malignancy in this series, papillary carcinoma was the most common variety (80%) followed by follicular carcinoma (20%).
Bangladesh J Otorhinolaryngol; October 2014; 20(2): 75-79
How to Cite
Manuscripts submitted for publication in the Bangladesh Journal of Otorhinolaryngology must not have been previously submitted or published. Accepted papers become the permanent property of the Bangladesh Journal of Otorhinolaryngology. By submitting a manuscript, the authors(s) agree that copyrights for their articles are automatically transferred to Bangladesh Journal of Otorhinolaryngology, if and when the articles are accepted for publication.
The use, in this journal, of registered trade names, trade marks, etc. without special acknowledgement does not imply that such names, as defined by the relevant protection laws, be regarded as unprotected, and, thus, free for general use.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).