Frequency of Malignancy in Multinodular Goitre


  • Mohammad Mostafizur Rahman Junior Consultant (ENT), Humna Upazila Health Complex, Comilla
  • Mohammad Idrish Ali Medical Officer, Department of Otolaryngology Head & Neck Surgery, BSMMU, Dhaka
  • Md Abdul Karim Junior Consultant (ENT), Institute of ENT, Dhaka
  • Mohammad Shaharior Arafat MS (ENT) Thesis Part, Department of Otolaryngology Head & Neck Surgery, DMCH, Dhaka
  • Mohammad Hanif Registrar, Department of Plastic & Reconstructive Surgery, NICRH, Dhaka
  • Kamrul Hasan Tarafder Professor, Deptt. of Otolaryngology Head & Neck Surgery, BSMMU, Dhaka



Malignancy, Multinodular Goiter


Objectives: To determine the frequency of thyroid carcinoma in clinically or sonogragraphically multinodular goitre in patients undergoing thyroidectomy

Setting: This is a cross sectional study was carried out at the Department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University during the period from January 2012 to June 2012.

Methods: This study includes all the patients admitted in Otolaryngology and Head-Neck surgery department of Bangabandhu Sheikh Mujib Medical University having diagnosis of multinodular goitre & underwent thyroidectomy. All patients with non-toxic multinodular goitre (clinically or sonographically) irrespective of age , sex was be included .

Results: Out of 50 patients, 41 patients (82%) were female, and 9 patients (18%) were male with a female to male ratio 4.5: 1. This shows female preponderance of multinodular goitre. Out of 50 patients, 5 patients had histologicaly proven thyroid malignancy (4 females and 1 male). In this study overall incidence of carcinoma in multinodular goitre was 10% and female to male ratio 4:1 with the incidence in female was 9.75% and in male 11.11. The incidence of malignancy under 21 years was 50% and above 21 years was 8.33%. Regarding the types of malignancy in this series, papillary carcinoma was the most common variety (80%) followed by follicular carcinoma (20%).


Bangladesh J Otorhinolaryngol; October 2014; 20(2): 75-79


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How to Cite

Rahman, M. M., Ali, M. I., Karim, M. A., Arafat, M. S., Hanif, M., & Tarafder, K. H. (2015). Frequency of Malignancy in Multinodular Goitre. Bangladesh Journal of Otorhinolaryngology, 20(2), 75–79.



Original Articles