Invasive Sinu-Naso-Orbital Aspergillosis Following Dacryocystorhinostomy In An Immunocompetent Patient: A Rare Case Report And Literature Review

Authors

  • Riad Habib Assistant professor, department of Neurosurgery, Enam Medical College & Hospital, Savar.
  • Nwoshin Jahan Department of Neurosurgery, Combined Military Hospital, Dhaka.
  • Atikur Rahman Associate Professor, Department of Neurosurgery, BSMMU
  • Nafaur Rahman Medical Officer, National Institute of Neurosciences and Hospital.
  • Ehsan Mahmood Ex-Department Head, Department of Neurosurgery, DMCH.
  • Md Farid Raihan Medical Officer, BSMMU

DOI:

https://doi.org/10.3329/bjns.v12i1.64012

Keywords:

DCR, dacryocystorhinostomy, invasive aspergillosis, sinu-naso-orbital lesion, vision loss

Abstract

Background: Invasive sino-naso-orbital aspergilloma is a rare disease with variable clinical features but in an immunocompetent patient it is rarely considered and often resulted in poor prognosis due to its diagnostic and therapeutic challenge. In this article we reported a rare case of invasive sinu-naso-orbital aspergillosis with intracranial extension following dacryocystorhinostomy (DCR). To our knowledge this is the only reported case in last 109 years.

Case Description: A 61 years old normotensive non diabetic male referred to us from an ophthalmologist with the complaints of retro-orbital pain followed by progressive dimness of vision later blindness on right eye after dacryocystorhinostomy.

Diagnosis and Intervention: His MRI reveals an isointense lesion in T1W and T2W image in right maxillary, ethmoidal sinus with orbital and retro-orbital and intracranial extension with heterogeneous contrast enhancement. Radiologist suggested a case of inflammatory pseudotumor and initially he was treated with steroid, due to lack of clinical response later antifungal was given but patient still was nonresponsive. The patient underwent right pterional craniotomy for biopsy and optic nerve decompression. Histopathology revealed aspergillus infection.  Post-operatively he was treated with voriconazole.

Lessons: Invasive sino-orbital aspergillosis is rare in immunocompetent patients. Early diagnosis is critical for successful management. Due to difficulty of diagnosis and higher mortality and morbidity, our recommendation is- ‘a patient with nonspecific complaints or retro-orbital pain’ should prompt the physician to consider this diagnosis.

Bang. J Neurosurgery 2022; 12(1): 47-52

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Published

2023-09-04

How to Cite

Habib, R. ., Jahan, N. ., Rahman, A. ., Rahman, N. ., Mahmood, E. ., & Raihan, M. F. . (2023). Invasive Sinu-Naso-Orbital Aspergillosis Following Dacryocystorhinostomy In An Immunocompetent Patient: A Rare Case Report And Literature Review. Bangladesh Journal of Neurosurgery, 12(1), 47–52. https://doi.org/10.3329/bjns.v12i1.64012

Issue

Section

Case Reports