CRISPR Technology- A New Horizon in Clinical Dentistry- A Review

Authors

  • Arnab Bhattacharyya Department Of Oral & Maxillofacial Pathology And Oral Microbiology, Kalinga Institute Of Dental Sciences, KIIT Deemed To Be University, Campus-5, Patia, Bhubaneswar, 751024
  • Harish Kumar Department Of Oral & Maxillofacial Pathology And Oral Microbiology, Kalinga Institute Of Dental Sciences, KIIT Deemed To Be University, Campus-5, Patia, Bhubaneswar, 751024
  • Pallavi Mishra Department Of Oral & Maxillofacial Pathology And Oral Microbiology, Kalinga Institute Of Dental Sciences, KIIT Deemed To Be University, Campus-5, Patia, Bhubaneswar, 751024
  • Abikshyeet Panda Department Of Oral & Maxillofacial Pathology And Oral Microbiology, Kalinga Institute Of Dental Sciences, KIIT Deemed To Be University, Campus-5, Patia, Bhubaneswar, 751024
  • Kailash Dash Department Of Oral & Maxillofacial Pathology And Oral Microbiology, Kalinga Institute Of Dental Sciences, KIIT Deemed To Be University, Campus-5, Patia, Bhubaneswar, 751024
  • Tamanna Adhikary Department Of Oral & Maxillofacial Pathology And Oral Microbiology, Kalinga Institute Of Dental Sciences, KIIT Deemed To Be University, Campus-5, Patia, Bhubaneswar, 751024

DOI:

https://doi.org/10.3329/bjms.v22i20.66305

Keywords:

CRISPR-Cas 9 system, Oral cancer, Genome editing

Abstract

Clustered Regularly InterSpaced Palindromic Repeats is known as CRISPR. It is a protein that can be programmed to change, eliminate, or activate the genome. This cutting-edge technology offers a broad range of possible implementation and is poised to revolutionise oral healthcare in the years to come. The most widely utilised genome editing techniques include homing endonucleases, Transcription Activator-Like Effector Nucleases, Zinc-Finger Nucleases, and CRISPR- CRISPR-associated protein 9 (Cas9). These adaptable genome-editing tools can alter the genomes in ways that are sequence-specific. Because it is highly effective and accurate, the genome editing method CRISPR-Cas9 has drawn attention as a potent weapon in the fight against cancer. This method and its uses, particularly in dental field, are covered in this review.

Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.42-46

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Published

2023-05-21

How to Cite

Bhattacharyya, A., Kumar, H., Mishra, P., Panda, A. ., Dash, K., & Adhikary, T. . (2023). CRISPR Technology- A New Horizon in Clinical Dentistry- A Review. Bangladesh Journal of Medical Science, 22(20), 42–46. https://doi.org/10.3329/bjms.v22i20.66305

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Original Articles