Does COVID-19 and oral, lung cancer have a connection? A insight to future investigation; A literature review.

Authors

  • Adhir Kumar Das 1Professor andhead of department of Pharmacology, Dhaka Medical College and Hospital, Dhaka, Bangladesh
  • Jahidul Islam 2Assistant professor of department of Pharmacology, UCSI University, Springhill, Port Dickson, Malaysia
  • Shahriar Jahan Post graduate student, University of Cyberjaya, Selangor, Malaysia
  • Afroza Sultana Post graduate student, University of Cyberjaya, Selangor, Malaysia
  • Sazia Nowshin Assistant Director ( Nursing and clinical service), Dhaka Central hospital, Dhaka

DOI:

https://doi.org/10.3329/bjms.v22i1.61862

Keywords:

SARS-CoV-2 virus; Viral infections; Oral and pulmonary malignancies.

Abstract

Even though there has been a significant amount of research conducted on the origin of SARSCoV- 2 (SARS-CoV-2) aetiology, very little is known about the disease’s long-term effects till the date(1). As with previous viral infections, SARS-CoV-2 may raise the risk of developing cancer by altering tumour suppressor genes and expression of various pro-oncogenic proteins. We will conduct a comprehensive review of the available research on it, because an infection with SARS-CoV-2 might have a potential to cause cancer in the long run, researchers are looking at the likelihood of this happening, precisely on likeliness of occurring oral and pulmonary malignancies in this work. We speculate that one of these long-term impacts may be the SARS-carcinogenic CoV-2 virus. The viral proteins Nsp-15 or Nsp-3 are hypothesised to have pro-oncogenic effects when they interact with two essential tumour suppressors, pRB and p53 inhibitors.

Bangladesh Journal of Medical Science Vol. 22 No. 01 January’23 Page : 15-21

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Published

2023-01-01

How to Cite

Das, A. K., Islam, J. ., Jahan, S. ., Sultana, A., & Nowshin, S. (2023). Does COVID-19 and oral, lung cancer have a connection? A insight to future investigation; A literature review. Bangladesh Journal of Medical Science, 22(1), 15–21. https://doi.org/10.3329/bjms.v22i1.61862

Issue

Section

Review Article