Comparison of two disk diffusion and E-test methods in determining antibiotic susceptibility of Pseudomonas aeruginosa strains in isolated burn infections of Ahvaz City

Authors

  • Changiz Ahmadizadeh Changiz Ahmadizadeh, Department of Microbiology, Science and Research Branch, Islamic Azad University, Ahar, Iran
  • Mehrdad Pashazadeh Department of Immunology, Faculties of Medicine Bursa Uludag University, Bursa, Turkey and Immunology Division, Department of Microbiology, Health Science Institute, Bursa Uludag University, Bursa, Turkey

DOI:

https://doi.org/10.3329/bjms.v19i4.46620

Keywords:

Pseudomonas aeruginosa, disk diffusion, E. test, antibiotic sensitivity

Abstract

Background: Pseudomonas aeruginosa with widely distributed in nature, for human beings is considered an opportunistic pathogen that causes infections of broad-spectrum, including administrative, respiratory, septicemia and bacteremia and sepsis in patients with the burning city of Ahvaz.

Method and Material: A total of 95isolates of Pseudomonas aeruginosa isolated from burn patients from January 2015 assemble and biochemical identification test, then they are antibiotic resistance in E. test and disk diffusion method were compared.

Findings: From 95 different clinical isolates of Pseudomonas aeruginosa isolated from E. test with the highest sensitivity to the antibiotic ceftazidime , 70(68/73%) and ciprofloxacin 50 (63/52%) and gentamicin 48 (52 /50 %) and the antibiotic imipenem 44 (31/46%) were sensitive and disk diffusion method antibiotic ceftazidime, 67(52/70%) and the antibiotic Ciprofloxacin 51(68/53%) and safety antibiotic imipenem 49(57/51%) and gentamicin 48(52/50%) were sensitive.

Conclusion: Statistically significant differences between E. test and disk diffusion antimicrobial susceptibility of there (p<0.05) and disk diffusion method can replace E. test, and also the most sensitive antibiotics, the antibiotics used The study of the isolated Pseudomonas is ceftazidime.

Bangladesh Journal of Medical Science Vol.19(4) 2020 p.646-651

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Published

2020-04-12

How to Cite

Ahmadizadeh, C., & Pashazadeh, M. (2020). Comparison of two disk diffusion and E-test methods in determining antibiotic susceptibility of Pseudomonas aeruginosa strains in isolated burn infections of Ahvaz City. Bangladesh Journal of Medical Science, 19(4), 646–651. https://doi.org/10.3329/bjms.v19i4.46620

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Section

Original Articles