Okra Infusion Water Improving Stress Oxidative and Inflammatory Markers on Hyperglycemic Rats
Objective: Okra has been known for its properties in improving diabetes markers. Most study used okra extract instead of its infusion water. Okra infusion water (OIW) contains polysaccharide and viscous fiber that delay gastric emptying, and help controlling glucose and HbA1C level. As the glucose low level, so does the inflammation and oxidative stress on hyperglycemic rats. This study aims to investigate the effect of OIW in improving glucose level, HbA1C, SOD and CRP levels.
Materials and methods: Posttest only control group design was applied to this experimental study using 15 male wistar rats divided randomly into 3 groups: Control, Streptozotocine (STZ), Streptozotocine+okra (OKRA). STZ, and OKRA groups induced with 65 mg/kg BW Streptozotocine and 110 mg/kg BW Nicotinamide on day 8. After the desirable glucose level achieved, OKRA were given 3.6 ml OIW on day 12-28. Data were analyzed using ANOVA in each variable.
Results: Fasting and Postprandial Glucose level of OKRA (137,40±3,57 mg/dL and 154.58±2.71 mg/dL), STZ (251,77±2,30 mg/dL and 270.18±3.03 mg/dL); HbA1C level of OKRA (7.93±0.25), STZ (21.29±0.65); SOD level of OKRA (55.292±3.77%), STZ (16.472±5.298%); CRP level of OKRA (1,540±0,059 mg/dL), STZ (2,230±0,093 mg/dL)
Conclusions: OIW able to improve glucose, HbA1C, SOD, and CRP level on hyperglycemic rats.
Bangladesh Journal of Medical Science Vol.18(4) 2019 p.748-752
Copyright (c) 2019 Tyagita N, Utami KP, Zulkarnain FH, Rossandini SM, Pertiwi NP, Rifki MA, Safitri AH
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:
- Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.
Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.