Markers of cardiovascular complications in patients with type 2 diabetes mellitus and arterial hypertension

Authors

  • Nadiia Demikhova Professor, Sumy State University, Department of family medicine
  • Olga Chernatska Sumy State University, Department of family medicine
  • Tetiana Mazur Sumy State University, Department of family medicine
  • Svetlana Bokova Sumy State University, Department of family medicine
  • Tetiana Rudenko Sumy State University, Department of family medicine
  • Lina Bumeister student. Sumy State University
  • Oleksii Demikhov PhD-student, Sumy State University, Department of management

DOI:

https://doi.org/10.3329/bjms.v17i2.35894

Keywords:

type 2 diabetes mellitus, arterial hypertension, albumin excretion rate, dyslipidemia, glycated hemoglobin

Abstract

Background: Hypertensive patients with type 2 diabetes mellitus are also at increased risk for diabetes mellitus–specific complications, including nephropathy. Even the smallest degree of albuminuria increases risk for cardiovascular diseases and all-cause death. The common conditions coexisting with type 2 diabetes (e.g., hypertension and dyslipidemia) are clear risk factors for cardiovascular diseases.

Methods and materials: The first (I) group consists of 99 obtained patients with type 2 and AH, the second (II) includes 49 practically healthy people. We evaluated such markers of cardiovascular complications as glycated hemoglobin, lipid profile components by biochemical method and albumin excretion rate with the help of enzyme immunoassay.

Result: The positive correlation between the level of albumin excretion rate and glycated hemoglobin (r = 0,23, p < 0,001) is confirmed that albuminuria is a main marker of diabetic nephropathy. The positive correlation between albuminuria and low density lipoproteins (r = 0,34, p < 0,001), triglycerides (r = 0,04, p < 0,001) is the definition of the important role of dyslipidemia in diabetic nephropathy.

Conclusion: Determination of albumin excretion rate, glycated hemoglobin as markers of nephropathy, lipid profile components is necessary for patients with type 2 diabetes mellitus and arterial hypertension for prevention cardiovascular complications.

Bangladesh Journal of Medical Science Vol.17(2) 2018 p.319-322

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Author Biography

Nadiia Demikhova, Professor, Sumy State University, Department of family medicine



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Published

2018-03-23

How to Cite

Demikhova, N., Chernatska, O., Mazur, T., Bokova, S., Rudenko, T., Bumeister, L., & Demikhov, O. (2018). Markers of cardiovascular complications in patients with type 2 diabetes mellitus and arterial hypertension. Bangladesh Journal of Medical Science, 17(2), 319–322. https://doi.org/10.3329/bjms.v17i2.35894

Issue

Section

Short Communication