Association of 25-hydroxyvitamin D and Anemia parameters in elderly with anemia of inflammation and non-inflammation

Authors

  • Vitasari Indriani Clinical Pathology Department, Faculty of Medicine, Jenderal Soedirman University
  • Nyoman Suci W Clinical Pathology Department, Faculty of Medicine, Diponegoro University
  • Herniah Asti W Clinical Pathology Department ,RSUP Dr Kariadi, Semarang

DOI:

https://doi.org/10.3329/bjms.v17i2.35889

Keywords:

elderly, anemia, 25-hydroxyvitamin D, hemoglobin, hematocrit, red blood cell count

Abstract

Background: Vitamin D deficiency and anemia are conditions commonly in eldery. Both result in significant morbidity in eldery. Relationship between 25-hydroxyvitamin D and anemia need to be concern, particularly in the elderly. including those characterized by inflammatory processes. The aim of this study is to analyze association and differentiations between of 25-hydroxyvitamin D levels and anemia parameters in elderly with anemia inflammation and non-inflammation.

Methods: An observational study, at Posyandu Lansia Puskesmas Sokaraja, was conducted among 40 subjects aged ≥60 years consecutively, between September - November 2015. 25-Hydroxyvitamin D, hemoglobin levels, hematocrit and red blood cell counts were measured. 25-Hydroxyvitamin D deficiency defined in level <30 ng/mL and anemia defined by the World Health Organization.

Results: After adjustment for CRP levels and leucocyte count, 25-Hydroxyvitamin D was inversely associated with anemia inflammation (p=0,018; p=0,010; p=0,000)and non-inflammation (p= 0,002; p=0,002; p=0,000). There was significantly differences 25-hydroxyvitamin D levels (p = 0.003) in elderly with anemia of inflammation and non-inflammation.

Conclusion: 25-Hydroxyvitamin D levels was associated with anemia inflammation and non-inflammation in eldery. Vitamin D may suppress inflammatory mechanism, and studies to determine whether chronic disease involves anemia inflamation are warranted.

Bangladesh Journal of Medical Science Vol.17(2) 2018 p.302-306

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Author Biography

Vitasari Indriani, Clinical Pathology Department, Faculty of Medicine, Jenderal Soedirman University



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Published

2018-03-23

How to Cite

Indriani, V., Suci W, N., & Asti W, H. (2018). Association of 25-hydroxyvitamin D and Anemia parameters in elderly with anemia of inflammation and non-inflammation. Bangladesh Journal of Medical Science, 17(2), 302–306. https://doi.org/10.3329/bjms.v17i2.35889

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Section

Original Articles