Protective Role of Nigerian Honey on Sperm indices and Testis in Sucrose-Fed Rats

Authors

  • Oluwakemi Tinuolaoluwa Oyelowo Department of Physiology, College of Medicine of the University of Lagos, Lagos
  • Daniel Abiodun Adekunbi Department of Physiology, Benjamin Carson (Senior) School of Medicine, Babcock University, Ilishan-Remo
  • Kayode A Dada Department of Physiology, College of Medicine of the University of Lagos, Lagos

DOI:

https://doi.org/10.3329/bjms.v13i2.18301

Keywords:

Nigerian honey, sucrose, sperm indices, antioxidants

Abstract

Objective: This study aimed at investigating the effect of high sucrose diet on male reproductive function and if Nigerian honey could exert a protective role.

Methods: Twenty-four (24) rats were randomly divided into four equal groups of six animals and given water (control); honey (H); high sucrose solution (30%w/v) (HSS); and both high sucrose solution (30%w/v) and honey (HSS+H). Each rat on honey received a daily dose of 10ml honey/kg/5ml of distilled water. Food intake, body weight, organ weight, fasting blood glucose, LH, FSH, testosterone and sperm functions were assessed.

Results: This revealed that sperm motility (p<0.05) and count increased in the HSS+ H and H- fed rats compared with HSS fed and control rats. Head and tail abnormalities sperm were also significantly reduced in the H fed rats (p<0.05).MDA level in the liver and not in the testes was significantly increased in the HSS fed rats compared with control while SOD activity was significantly increased in HSS+H rats compared with the HSS fed rats.

Conclusion: The results indicate that sucrose feeding impact negatively on sperm function while Nigerian honey supplementation confers protective function on male reproduction.

DOI: http://dx.doi.org/10.3329/bjms.v13i2.18301

Bangladesh Journal of Medical Science Vol.13(2) 2014 p.180-189

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Published

2014-03-10

How to Cite

Oyelowo, O. T., Adekunbi, D. A., & Dada, K. A. (2014). Protective Role of Nigerian Honey on Sperm indices and Testis in Sucrose-Fed Rats. Bangladesh Journal of Medical Science, 13(2), 180–189. https://doi.org/10.3329/bjms.v13i2.18301

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Original Articles