An elderly lady with multiple blisters all over the body: Hailey Hailey Disease

  • Tanzina Nuhat Sharma Honorary Medical Officer, Dpt of Medicine, Dhaka Medical College and Hospital, Dhaka
  • Lima Saha Intern doctor, Dhaka Medical College and Hospital, Dhaka
  • Mohiuddin Sharif Medical Officer, Dpt of Medicine, Dhaka Medical College and Hospital, Dhaka
  • Md Mahfuzul Haque Consultant of Medicine, Dhaka Medical College and Hospital, Dhaka
  • Md Robed Amin Associate Professor of Medicine, Dhaka Medical College, Dhaka
Keywords: elderly lady, multiple blisters

Abstract

Hailey-Hailey disease (HHD) is an autosomal-dominant genodermatosis, associated with abnormal epithelial cell adhesion due to altered calcium metabolism. Clinical features involve painful red blisters, erosions, fissured and hypertrophic plaques predominantly in the intertriginous areas. Heat, friction, minor trauma, superimposed bacterial or viral infection can aggravate the condition. Here, we report a case of a 50-year old lady with no previous family history presented with severe attack of HHD since last 5 months. Histology showed acantholysis of keratinocytes resembling characteristic dilapidated brick wall appearance in the epidermis layer of skin which helped for the confirmed diagnosis.

Bangladesh J Medicine Jan 2020; 31(1) : 29-32

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Abstract
421
PDF
109
Published
2019-12-30
How to Cite
Sharma, T., Saha, L., Sharif, M., Haque, M. M., & Amin, M. R. (2019). An elderly lady with multiple blisters all over the body: Hailey Hailey Disease. Bangladesh Journal of Medicine, 31(1), 29-32. https://doi.org/10.3329/bjm.v31i1.44750
Section
Case Reports